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3 (0,058s)

Result

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

gene-like 1 (PLAGL1) gene in 19 of 20 of the samples analyzed, with the most common fusion being EWSR1:PLAGL1 (n = 13). Five tumors showed a PLAGL1:FOXO1 fusion and one a PLAGL1:EP300 fusion. High transcript level...

Neurosciences (including psychophysiology)

  • 2021
  • Jimp
  • Link
Result

Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

PLAGL1 or PLAGL2, and an absence of recurrent genetic alterations characteristic, and synaptophysin). Tumors with PLAGL1 amplification were typically diagnosed during adolescence% for PLAGL1-amplified tumors, 25% for PLAGL...

Oncology

  • 2023
  • Jimp
  • Link
Result

Aetiology and treatment of neonatal diabetes

, or PLAGL1 gene imprinting on chromosome 6q. Rarely, neonatal diabetes can be a part...

Endocrinology and metabolism (including diabetes, hormones)

  • 2019
  • JSC
  • Link
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