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177 808 (0,25s)

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Active pharmaceutical ingredients available as substances for extemporaneous preparation in veterinary medicine in the Czech republic

about new possibilities of drug compounding.In veterinary medicine, extemporaneously prepared drugs can be also used in therapy. In the recent four years the selection of suitable compounds for extemporan...

FR - Farmakologie a lékárnická chemie

  • 2014
  • Jx
  • Link
Result

A new class of antitumour coordination compounds of Pt(II)?

Possibilities of anticancer drugs function and chosen methods of DNA-anticancer drug interaction research are described in the article in a very simple way, acceptable also for non-physicians. Results of a new class of Pt(I...

BO - Biofyzika

  • 2002
  • D
Result

Molecular docking study of potential drug candidates against borreliosis

as a possible drug target compound and therefore it should be further examined there is an extensive need to find a new drug. For this purpose our in silicodocking study was carried out to identify drug

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2017
  • D
Result

in vitro and in silico Studies of Interaction of Synthetic 2,6,9-Trisubstituted Purine Kinase Inhibitors BPA-302, BP-21 and BP-117 With Liver Drug-Metabolizing Cytochromes P450

An evaluation of possible interactions with enzymes of drug metabolism, on the properties of any drug or biologically active compound. The article is focused with significant anticancer activities which we have dev...

Organic chemistry

  • 2020
  • Jimp
  • Link
Result

In vitro and in silico studies of interaction of synthetic 2,6,9-trisubstituted purine kinase inhibitors BPA-302, BP-21 and BP-117 with liver drug-metabolizing cytochromes P450

An evaluation of possible interactions with enzymes of drug metabolism, on the properties of any drug or biologically active compound. The article is focused with significant anticancer activities which we have dev...

Pharmacology and pharmacy

  • 2020
  • Jimp
  • Link
Result

"Drug-likeness" properties of natural compounds

compared with synthetic, semisynthetic compounds and the Food and Drug Administration relationship for classifying drugs from nondrugs and natural compounds from nonnatural ones behind "drug-likeness...

Organic chemistry

  • 2019
  • Jimp
  • Link
Result

Intoxications of horses

Intoxications of animals can be caused by anorganic and organick toxikants, mykotoxins, fytotoxins, bacterial toxins, cyanotoxins, zootoxins, drugs and other compounds. This chapter summarizes the informationes about possibiliti...

FR - Farmakologie a lékárnická chemie

  • 2008
  • C
Result

Probes &Drugs portal: an interactive, open data resource for chemical biology

The Probes & Drugs portal is a public resource joining together focused libraries of bioactive compounds (probes, drugs, specific inhibitor sets etc.) with commercially available screening libraries. The purpose of the port...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2017
  • R
  • Link
Result

Separation of precursors of basic drugs by capillary liquid chromatography

separation of basic compounds by RP CLC...

CB - Analytická chemie, separace

  • 2002
  • D
Result

Possible interactions of analgesics with liver microsomal cytochromes P450

Cytochromes P450 (CYP), the most important enzymes of phase I of drug metabolism, are involved in the biotransformation of many drugs used in the treatment of pain. Knowledge of the metabolic pathways of drugs is essential ...

FP - Ostatní lékařské obory

  • 2009
  • Jx
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