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Ligand-Based Pharmacophore Modeling Using Novel 3D Pharmacophore Signatures
Pharmacophore modeling is a widely used strategy for finding new hit molecules, a 3D pharmacophore ligand-based modeling approach to search for pharmacophores. The approach searches for 3D pharmacophor...
Biochemistry and molecular biology
- 2018 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
2D Pharmacophore Query Generation
and compiled into a 3D pharmacophore model. However, in many cases the structures of the ligands are not known which results in using a 2D pharmacophore model. We introduce a method capable of automatic generation...
IN - Informatika
- 2014 •
- D •
- Link
Rok uplatnění
D - Stať ve sborníku
Výsledek na webu
Probabilistic Approach for Virtual Screening Based on Multiple Pharmacophores
Pharmacophore modeling is a widely used approach for the discovery of new biologically active compounds. According to the IUPAC definition, pharmacophore of successful applications of pharmacophore models ...
Biochemistry and molecular biology
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Comprehensive Comparison of the Ergot Alkaloids Family with 5-HT Receptor Pharmacophore Models
Comprehensive Comparison of the Ergot Alkaloids Family with 5_HT Receptor Pharmacophore Models...
CC - Organická chemie
- 2000 •
- A
Rok uplatnění
A - Audiovizuální tvorba
Comprehensive Comparison of the Ergot Alkaloids Family with 5 -HT Receptor Pharmacophore Models.
Comprehensive Comparison of the Ergot Alkaloids Family with 5-HT Receptor Pharmacophore Models...
CC - Organická chemie
- 2000 •
- D
Rok uplatnění
D - Stať ve sborníku
Pharmacophore Modelling Used in Rational Drug Design
and is mainly focused on pharmacophore modelling, one of the modern approaches in drug...
Organic chemistry
- 2016 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Use of 3D QSAR Pharmacophore Modelling in the Research of Influenza
, higher safety and increased tolerability. A pharmacophore is a set of structural at a receptor site and its biological activity. In the current work, 3D pharmacophore based pharmacophoric features present in the active s...
Biochemistry and molecular biology
- 2016 •
- D •
- Link
Rok uplatnění
D - Stať ve sborníku
Výsledek na webu
In silico pharmacophore modeling on known pyridinium oxime reactivators of cyclosarin (GF) inhibited AChE to aid discovery of potential, more efficacious novel non-oxime reactivators
of novel antidotes for GF toxicity, a three-dimensional in silico pharmacophore model for reactivation efficacy against GF intoxication is presented. The model was generated from. The generated pharmacophore m...
FR - Farmakologie a lékárnická chemie
- 2013 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Antimycobacterial activita of compounds with basic pharmacophore. Piperidinoesters of phenylcarbamoyl acid.
New basic pharmacophore of antimycobacterial activity...
CC - Organická chemie
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Calculations of Resonance substituent Constatnts of some Important Pharmacophore Groups
Calculations of Resonance Substituent Constatnts of some Important Pharmacophore Groups...
CC - Organická chemie
- 2001 •
- D
Rok uplatnění
D - Stať ve sborníku
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