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5 313 (0,071s)

Result

Precise determination of primary cytogenetic abnormalities provides added value for stratification of chronic lymphocytic leukemia patients

on cytogenetic abnormalities occurring in isolation is robust; however, the performance of patients with two or more cytogenetic abnormalities is heterogeneous and information determination of primary cytogene...

Biological sciences

  • 2019
  • Jimp
  • Link
Result

Our experience with the detection of cytogenetic abnormalities that may be important diagnostic aids in some chilhood solid tumors, especially in bone and soft tissue sarcomas

Our experience with the detection of cytogenetic abnormalities that may be important diagnostic aids in some chilhood solid tumors, especially in bone and soft tissue sarcomas....

FD - Onkologie a hematologie

  • 2004
  • D
Result

Cytogenetics and molecular cytogenetics of acute leukaemias

Main mehods, interpretation and findings of classic cytogenetics and methods of molecular genetics in acute leukaemias are described.

FD - Onkologie a hematologie

  • 2002
  • Jx
Result

Cytogenetics

Main methods, interpretation and findings of classic cytogenetics and methods of molecular genetics in leukemias are reviewed in this chapter of the monograph....

FD - Onkologie a hematologie

  • 2002
  • C
Result

Cytogenetic abnormalities predict survival after allogeneic hematopoietic stem cell transplantation for pediatric acute myeloid leukemia: a PDWP/EBMT study

Poor-risk (PR) cytogenetic/molecular abnormalities generally direct pediatric cytogenetic abnormalities. In a multivariable model, 11q23 (hazard ratio [HR] = 0.66, P = 0.03) and other PR cytogenetic ab...

Hematology

  • 2024
  • Jimp
  • Link
Result

The importance of classical cytogenetic examination in clinical paediatric practice: analysis of 384 indications

Numerical and structural chromosomal abnormalities represent an important group cytogenetic examination under the light microscope. During the 2010-2012 time periodthe classical cytogenetic examination was performed in 384 ...

EB - Genetika a molekulární biologie

  • 2014
  • Jx
  • Link
Result

Complex karyotypes in childhood acute lymphoblastic leukemia: cytogenetic and molecular cytogenetic study of 21 cases

Cytogenetic and molecular cytogenetic analysis of 79 childhood acute lymphoblastic leukemias (ALL) revealed chromosomal abnormalities in 76 (96%)....

FD - Onkologie a hematologie

  • 2003
  • Jx
Result

Rele of classical and molecular cytogenetics for diagnosis of multiple myeloma

Chromosomal abnormalities are one of the most important and independent prognostic factor in patients with multiple myeloma. Classical cytogenetics based of malignant plasma cells. In order to circumvent this pitfall, molecular ...

EB - Genetika a molekulární biologie

  • 2008
  • Jx
Result

The Impact of Cytogenetic abnormalities in relapsing multiple myeloma patients treated by new types of drugs

In this paper we show an example of use the detection of chromosomal abnormalities (deletion 13q14, translocation t(4;14), deletion 17q13 and gain 1q21) using modified fluorescence in situ hybridization (FISH) and following searching for the...

FD - Onkologie a hematologie

  • 2008
  • Jx
Result

Ixazomib significantly prolongs progression-free survival in high-risk relapsed/refractory myeloma patients

Certain cytogenetic abnormalities are known to adversely impact outcomes cytogenetic abnormalities were defined as del(17p), t(4;14), and/or t(14;16); additionally cytogenetic results; 137 (25%) had high-r...

Hematology

  • 2017
  • Jimp
  • Link
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