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An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors
Our data provide evidence that the FGF-dependent generation of ameloblasts from self-renewing stem cells in postnatal mice is preceded by an embryonic phase during which ameloblasts arise from a progenitor population that is less de...
EB - Genetika a molekulární biologie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Temporal analysis of ectopic enamel production in incisors from sprouty mutant mice
The mouse incisor has two unusual features: it grows continuously and it is covered by enamel exclusively on the labial side. Ameloblasts and enamel were detected on the lingual side in postnatal Spry2(+/-); Spry4(+/-) incisors....
EB - Genetika a molekulární biologie
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Ameloblastic fibrosarcoma: clinicopathological and molecular analysis of seven cases highlighting frequent BRAF and occasional NRAS mutations
Aims Ameloblastic fibrosarcoma (AFS) is an aggressive odontogenic neoplasm featuring malignant mesenchymal stroma in addition to an ameloblastic epithelial component, and is hence considered to be the malignant counterpart of am...
Pathology
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Metastasizing ameloblastoma, or ameloblastic carcinoma? A case report including genetic analysis
Ameloblastic carcinoma and metastasizing ameloblastoma are rare tumors of odontogenic origin. While ameloblastic carcinoma exhibits microscopic features analyses uncovered a metastasizing tumor with features of ameloblastic...
Dentistry, oral surgery and medicine
- 2022 •
- O
Rok uplatnění
O - Ostatní výsledky
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
Ameloblasts are specialized epithelial cells in the jaw that have ameloblast-derived proteins that function as a scaffold for hydroxyapatite crystals. The loss of function of ameloblast-derived proteins results in a group o...
Biochemistry and molecular biology
- 2023 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Caspase-7 participates in differentiation of cells forming dental hard tissues
Apoptosis during tooth development appears dependent on the apoptotic executioner caspase-3, but not caspase-7. Instead, activated caspase-7 has been found in differentiated odontoblasts and ameloblasts, where it does not correlate with apop...
EB - Genetika a molekulární biologie
- 2013 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Localization of c-Myb in differentiated cells during postnatal molar and alveolar bone development
of this protein in differentiated ameloblasts, odontoblasts and osteoblasts. In addition, c...
EA - Morfologické obory a cytologie
- 2012 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Metastasising ameloblastoma or ameloblastic carcinoma? A case report with mutation analyses
a metastasising tumour with features of ameloblastic carcinoma, which developed from of ameloblastic carcinoma associated with an alteration of Wnt signalling and the presence......
Dentistry, oral surgery and medicine
- 2023 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Bioinformatic analysis and molecular modelling of human ameloblastin suggest a two-domain intrinsically unstructured calcium-binding protein
Ameloblastin (AMBN) was originally believed to be an enamel-specific extracellular matrix glycoprotein secreted by ameloblasts. Recently, AMBN expression was also detected in developing mesenchymal dental hard tissues, in trauma-induced repa...
CF - Fyzikální chemie a teoretická chemie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Mouse Incisor Stem Cell Niche and Myb Transcription Factors
Dental hard tissues are formed particularly by odontoblasts (dentin) and ameloblasts (enamel). Whereas the reparation of dentin is often observed, enamel does not regenerate in most species. However, in mouse incisor, a population of somatic...
EB - Genetika a molekulární biologie
- 2015 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
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