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13 351 (0,833s) •

Projekt

Role of the 14-3-3 protein in the regulation of phosducin function (GAP305/11/0708)

The main goal is to study the structural basis for the 14-3-3 protein-dependent and Ser73 and the binding to the regulatory 14-3-3 protein. The detailed mechanism of the 14-3-3 protein-dependent inhibition of phosducin func...

EB - Genetika a molekulární biologie

  • 2011 - 2015
    • •
  • 6 340 tis. Kč
    • •
  • 6 340 tis. Kč
    • •
  • GA ČR
Projekt

Condensed Macropolyhedral Group 14 to Group 16 Heteroboranes. (GA203/94/0362)

9J - 9

  • 1994 - 1996
    • •
  • 267 tis. Kč
    • •
  • 397 tis. Kč
    • •
  • GA ČR
Projekt

"Czech Republic at CERN! 11.- 14. 6. 1996 (PG96254)

9T - 9

  • 1996 - 1996
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MŠMT
Projekt

14-3-3 protein dependent regulation of caspase-2 (GA17-00726S)

. Phosphorylated procaspase-2 (proC2) binds to the 14-3-3 protein and this interaction blocks mechanism we propose to: i) verify sites responsible for the 14-3-3 protein binding to proC2, ii) perform biophysical characterization of ...

EB - Genetika a molekulární biologie

  • 2017 - 2019
    • •
  • 8 069 tis. Kč
    • •
  • 7 580 tis. Kč
    • •
  • GA ČR
Projekt

Study of the interaction between 14-3-3 protein and regulator of G protein signaling RGS3. (IAA501110801)

The main goal of this project is to understand the structural basis of 14-3-3 protein?dependent regulation of function of RGS3 protein. 14-3-3 proteins known to be 14-3-3 binding partners. The role of 14-3-3 protei...

BO - Biofyzika

  • 2008 - 2012
    • •
  • 5 095 tis. Kč
    • •
  • 5 095 tis. Kč
    • •
  • AV ČR
Projekt

Molecular basis of regulation of cyclin-dependent kinase CDK16 by 14-3-3 proteins (GA25-15222S)

to a complex of phosphorylated cyclin Y (pCCNY) with 14-3-3 proteins. Thus, CDK16. Additionally, CDK16 also directly interacts with 14-3-3 proteins, although the function mechanism of CDK16 regulation and the role of 14-3-...

Biochemistry and molecular biology

  • 2025 - 2027
    • •
  • 12 110 tis. Kč
    • •
  • 12 001 tis. Kč
    • •
  • GA ČR
Projekt

Role of the phosphorylation and the 14-3-3 protein binding in the regulation of signaling complexes function (GA204/06/0565)

The overall goal of this project is to understand the structural basis of 14-3 signaling complexes: 14-3-3 protein/forkhead transcription factor FoxO4 and 14-3-3 protein/tyrosine hydroxylase complex. 14-3-3 protein...

BO - Biofyzika

  • 2006 - 2008
    • •
  • 2 802 tis. Kč
    • •
  • 2 802 tis. Kč
    • •
  • GA ČR
Projekt

Study of the molecular mechanism of 14-3-3 isoform binding specificity (KJB5011308)

The 14-3-3 proteins are a family of regulatory molecules, which specifically, the 14-3-3 proteins play key regulatory roles in signal transduction, cell cycle of 14-3-3 isoform binding specificity, which are still unresolve...

CE - Biochemie

  • 2003 - 2005
    • •
  • 2 578 tis. Kč
    • •
  • 2 004 tis. Kč
    • •
  • AV ČR
Projekt

Molecular basis of the 14-3-3 protein-dependent regulation of protein kinase activity (GA19-00121S)

14-3-3 proteins, a family of highly conserved dimeric proteins ubiquitously of how the 14-3-3 proteins regulate the activity of these protein kinases is, in most to investigate the molecular mechanisms underlying the 14-3-3...

Biochemistry and molecular biology

  • 2019 - 2023
    • •
  • 8 340 tis. Kč
    • •
  • 8 034 tis. Kč
    • •
  • GA ČR
Projekt

Edition of Processings of I symposium of theatre antropology in Brno 14-16 december 1995 (PG96345)

AL - Umění, architektura, kulturní dědictví

  • 1996 - 1996
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MŠMT
  • 1 - 10 z 13 351