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50 674 (0,231s) •

Result

beta-Arrestin Interacts with the Beta/Gamma Subunits of Trimeric G-Proteins and Dishevelled in the Wnt/Ca2+ Pathway in Xenopus Gastrulation

beta-Catenin independent, non-canonical Wnt signaling pathways play a major and beta-Catenin independent signaling cascades including the Wnt/Planar Cell Polarity in the Wnt/beta-Catenin and the W...

EB - Genetika a molekulární biologie

  • 2014
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  • Jx
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  • Link
Result

Beta-Arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways

signaling components such as beta-arrestin and casein kinase 1 and 2 (CK1 and 2) can contribute to determine signaling specificity in beta-catenin-independent WNT signalingRecent advances in understanding...

EB - Genetika a molekulární biologie

  • 2008
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  • Jx
Result

Sequential activation and inactivation of dishevelled in the Wnt/{beta}-catenin pathway by casein kinases.

Dishevelled (Dvl) is a key component in the Wnt/beta-catenin signaling pathway for the activation of downstream signaling. Upon pathway activation by Wnts, Dvl becomes/beta-catenin signaling

ED - Fyziologie

  • 2011
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  • Jx
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Result

Receptor tyrosine kinases activate canonical WNT/beta catenin signaling via MAP kinase/LRP6 pathway and direct beta-Catenin phosphorylation

Receptor tyrosine kinase signaling cooperates with WNT/beta catenin signaling in regulating many biological processes, but the mechanisms of their interaction remain poorly defined. We describe a potent activation of WNT/

ED - Fyziologie

  • 2012
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  • Jx
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Result

Beta-arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?

Beta-arrestins were originally identified as negative regulators of G protein-coupled receptor signalling, which can also serve as intracellular scaffolds and signalling intermediates. Here, we summarize the importance of <...

BO - Biofyzika

  • 2010
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  • Jx
Result

A subset of human pancreatic beta cells express functional CD14 receptors: a signaling pathway fot beta cell-related glycolipids, sulfatide and beta-galactosylceramide

We described functional CD14 expression on a subset of human beta-cells and its involvement in signalling of beta cell-related glycolipids - sulfatide and beta-galactosylceramide......

EE - Mikrobiologie, virologie

  • 2010
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  • Jx
Result

Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells

evidence for multiple crosstalk between Hippo and Wnt/beta-catenin signalling. By upregulating Wnt pathway agonists, the alternative Wnt signalling can inhibit the canonical signalling, in both healthy an...

Biochemistry and molecular biology

  • 2018
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  • Jimp
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Result

Role of the transforming growth factor (TGF)-beta signal pathway in haematopoiesis and studies of new inhibitors of this pathway in the treatment of lower-risk myelodysplastic syndrome

and down-stream intracellular signalling molecules. TGF-beta receptor activationTransforming growth factor (TGF)- beta is a cytokine originally named for its ability to transform normal fibroblasts in culture. TGF-beta...

Hematology

  • 2019
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  • JSC
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  • Link
Result

Biotin-rich, optically clear nuclei express estrogen receptor-beta: Tumors with morules may develop under the influence of estrogen and aberrant beta-catenin expression

The present study indicates that N/C co-localization of ER-beta and beta-catenin is a feature common to the morules with BROCN that appear in the BROCN-family tumors from various anatomic sites. Whether the estrogen-signaling

FP - Ostatní lékařské obory

  • 2007
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  • Jx
Result

Wnt Signaling Pathway in Mammary Gland Development and Carcinogenesis

The signaling pathway mediated by Wingless-type (Wnt) proteins is highly conserved in evolution. This pivotal pathway is known to regulate cell fate decisions, cell proliferation, morphology, migration, apoptosis, different...

FD - Onkologie a hematologie

  • 2006
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  • Jx
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