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2 067 (0,087s)

Result

Genic and chromosomal components of Prdm9-driven hybrid male sterility in mice (Mus musculus)

- to- repair double-strand breaks, incomplete synapsis of homologous chromosomes in vertebrates, predetermines the sites of recombination between homologous chromosomes and their synapsis in early meiotic prophase....

Genetics and heredity (medical genetics to be 3)

  • 2022
  • Jimp
  • Link
Result

Cisplatin-induced DNA double-strand breaks promote meiotic chromosome synapsis in PRDM9-controlled mouse hybrid sterility

synapsis and hybrid male sterility. We have previously reported that Prdm9-controlled processed DSBs by improving meiotic chromosome synapsis with exogenous DSBs. A single at the zygotene stage of sterile hybrids, enhanced homo...

Genetics and heredity (medical genetics to be 3)

  • 2018
  • Jimp
  • Link
Result

Prdm9 deficiency of rat oocytes causes synapsis among non-homologous chromosomes and aneuploidy

-homologous synapsis (NHS). HORMAD2 protein serves as a barrier to sister-chromatid repair and a signal for the synapsis and DNA repair checkpoints. NHS but not asynapsis with homologous synapsis. NHS was ...

Biochemistry and molecular biology

  • 2022
  • Jimp
  • Link
Result

Identification of ASYNAPTIC4, a Component of the Meiotic Chromosome Axis

. Establishment of the axis is essential for the subsequent synapsis of the homologous axis formation and were unable to complete synapsis. Although the initiation. Furthermore, our data suggest that ASY3/ASY4 are the funct...

Plant sciences, botany

  • 2018
  • Jimp
  • Link
Result

Meiotic chromosome dynamics and double strand break formation in reptiles

and synapsis of homologous chromosomes to recombination, which are essential dynamics, including chromosome pairing, synapsis and the formation of double strand with telomeres clustering forming the bouquet, which we propo...

Zoology

  • 2022
  • Jimp
  • Link
Result

Meiotic behaviour of evolutionary sex-autosome translocations in Bovidae

). The autosomal regions of fused sex chromosomes showed normal synapsis with their homologous counterparts. Synapsis in the pseudoautosomal region (PAR) leads to the formation evolution suggests common mechanisms enabling ...

EB - Genetika a molekulární biologie

  • 2016
  • Jx
  • Link
Result

Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse

of fertility phenotypes correlated with the rate of failure of synapsis between homologous and sperm count, correlated with increasing difficulties of meiotic synapsis of homologous chromosomes and with meiotic ar...

Genetics and heredity (medical genetics to be 3)

  • 2020
  • Jimp
  • Link
Result

Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

) homology fully restored synapsis in a given autosomal pair, and we predicted that two of meiotic chromosome synapsis and infertility in male hybrids that are the offspring stretches of consubspecific homology on ...

Genetics and heredity (medical genetics to be 3)

  • 2018
  • Jimp
  • Link
Result

Synapsis naxiorum sp. n. from Yunnan (Coleoptera: Scarabaidae)

Synapsis naxiorum sp. n. from Yunnan (Coleoptera: Scarabaidae)...

EG - Zoologie

  • 2000
  • Jx
Result

Meiotic Recognition of Evolutionarily Diverged Homologs: Chromosomal Hybrid Sterility Revisited

mutual recognition of homologous chromosomes and disrupt their synapsis. Unsynapsed or mispaired homologs can induce early meiotic arrest, or their random segregation can cause aneuploidy of spermatids and sperm cells. Imp...

Biochemistry and molecular biology

  • 2023
  • Jimp
  • Link
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