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The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling
receptor type O (PTPRO) is down-regulated in a subset of colorectal cancer (CRC) patients witha poor prognosis. Here we identified PTPRO as a phosphatase activation triggered by PTPRO down-regulation induces phosphorylatio...
FD - Onkologie a hematologie
- 2014 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Reply to Hernandez et al. - GWAS of acute renal graft rejection
We were able to identify and validate the association of 2 genetic loci (CCDC67 and PTPRO) with biopsy-proven T cell–mediated rejection (TCMR). We concentrated our efforts on building a discovery cohort of cases with very low immunological r...
Human genetics
- 2018 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Genome-Wide Association Study of Acute Renal Graft Rejection
in both univariate and multivariate analysis. One locus encompasses PTPRO, coding...
Urology and nephrology
- 2017 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
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