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63 809 (0,145s)

Result

Zjednodušené metody pro funkcionalizaci 3-hexoxythiofenů v poloze 5 a jejich další reakce na alkynyl a vinyl deriváty

Kinetically controlled lithiation of 3-hexoxythiophene in the 5-position allows the synthesis of interesting functionalised building blocks after reaction with N,N-dimethylformamide and iodine....

CC - Organická chemie

  • 2009
  • Jx
Result

Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function

Background: The 14-3-3 protein binds to and regulates the function of the regulator of G protein signaling 3 (RGS3). Results: The 14-3-3 binding affects the structure of the G? interaction portion of RGS3....

BO - Biofyzika

  • 2011
  • Jx
  • Link
Result

Structural Biology of 14-3-3 Proteins

14-3-3 proteins are abundant regulatory proteins involved in many biologically important processes. 14-3-3 proteins function as scaffold molecules modulating the activity of their binding partners....

CF - Fyzikální chemie a teoretická chemie

  • 2003
  • Jx
Result

Efficient 2 S-3 positronium production by stimulated decay from the 3 P-3 level

S-3 positronium atoms by driving the 1 S-3-3 P-3 and 3 P-3-2 S-3 transitions, overcoming the natural branching ratio limitation of spontaneous decay from 3 P-3 to 2 S-<...

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2019
  • Jimp
  • Link
Result

Structural biology of 14-3-3 proteins

Short introduction concerning structural biology of regulatory 14-3-3 proteins.

BO - Biofyzika

  • 2003
  • D
Result

3´-deoxy-3´-[18F]fluorothymidin, injection

Internal production prescription of the 3´-deoxy-3´-[18F]fluorothymidin, injection.

CH - Jaderná a kvantová chemie, fotochemie

  • 2005
  • O
Result

Contribution to the stereoselective synthesis of (3 ' S)-3 '-isothiocyanato-3 '-C-vinyl-3 '-deoxyuridine and its derivatives

A stereoselective synthesis of the (3'S)-3'-isothiocyanato-3'-C-vinyl-3'-deoxyuridine via (3,3)sigmatropic rearrangement of allylic thiocyanate derived from protected uridine was investigated....

CC - Organická chemie

  • 2005
  • Jx
Result

Straightforward synthesis of 3´-deoxy-3´,4´-didehydronucleoside-5´-aldehydes via 2´,3´-O-orthoester group elimination: a simple route 3´,4´-didehydronucleosides

Straightforward, high-yielding syntheses of 3´-deoxy-3´,4´-didehydronucleoside-5´-aldehydes and 3´-deoxy-3´,4´-didehydronucleosides starting from 2´,3´-orthoester derivatives of ribonucleosides are describ...

CC - Organická chemie

  • 2010
  • Jx
Result

Two 14-3-3 Binding Motifs Are Required for Stable Association of Forkhead Transcription Factor FOXO4 with 14-3-3 Proteins and Inhibition of DNA Binding

In this study, we have quantitatively characterized the in vitro interactions among 14-3-3, the Forkhead transcription factor FOXO4, and its target DNA, the insulin response element....

BO - Biofyzika

  • 2003
  • Jx
Result

14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2)

an association with the scaffolding protein 14-3-3. However, the role of 14-3-3 CaMKK2 and the 14-3-35 gamma protein, as well as the architecture of their complex data suggest that the 14-3-3...

Physical chemistry

  • 2018
  • Jimp
  • Link
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