All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

43 960 (0,264s) •

Result

Abnormal polyadenylation in diseases

Mutations in the poly(A) signal (AAUAAA hexamer) present in the globin pre-mRNA we identified in hematological disorders caused by defects in the synthesis of one or more of the globin chains (thalassemia)....

Hematology

  • 2019
    • •
  • C
    • •
  • Link
Result

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth

signaling for tumor progression in the context of acquired KRAS and other mutations, that reduce Wnt/?-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN and display approximately 50% inhibition...

EB - Genetika a molekulární biologie

  • 2013
    • •
  • Jx
    • •
  • Link
Result

The AIB1 gene polyglutamine repeat length polymorphism and the risk of breast cancer development

(poly-Q) repeat length polymorphism of the amplified in breast cancer 1 (AIB1) gene was analyzed as a risk factor influencing BC onset in BRCA1/2 mutation carriers with contradictory results. We genotyped AIB1 poly-Q repea...

FD - Onkologie a hematologie

  • 2011
    • •
  • Jx
    • •
  • Link
Result

Mutations in EGFR signal pathway in correlation with response to treatment of head and neck cancers

Presentation of study - mutation in EGFR signal pathway in correlation with treatment of head and neck cancers...

FF - ORL, oftalmologie, stomatologie

  • 2009
    • •
  • Jx
Result

Specifics of ovarian cancer in patients with BRCA mutations: PARP Inhibitor Treatment in Ovarian and Breast Cancer

Relationship BRCA germline mutations to the incidence of ovarian cancer is well known. The lifetime risk of development ovarian cancer is among BRCA1 gene mutation carriers 60 % and of BRCA2 gene mutation carriers around 10...

FK - Gynekologie a porodnictví

  • 2014
    • •
  • Jx
Result

Single-Site Mutational Engineering and Following MonoPEGylation of the Human Lectin Galectin-2: Effects on Ligand Binding, Functional Aspects, and Clearance from Serum

prompted us to characterize the effect of monosubstitution with poly(ethylene glycol as counterreceptors in vitro and tissue sections. PEGylation led to decreases in affinity/signal intensity with context dependence. The introducti...

CE - Biochemie

  • 2013
    • •
  • Jx
    • •
  • Link
Result

Mutations in EGFR signal pathway in correlation with response to treatment of head and neck cancers

prognostic and predictive value of EGFR expression and some genetic alterations in EGFR signal patway were investigated in our study...

FF - ORL, oftalmologie, stomatologie

  • 2011
    • •
  • Jx
Result

Using of AM and FM Signal for ADC Testing

In this paper qualities of methods for testing dynamical parameters of A/D converters with poly-harmonics signals are analyzed. As source for these signals amplitude and frequency modulation signals are used. These...

JB - Senzory, čidla, měření a regulace

  • 2010
    • •
  • D
Result

Poly(luminol) based sensor array for determination of dissolved chlorine in water

signal provided by thin immobilized poly(luminol) reagent layer. The poly(luminol for preparation of the poly(luminol) layer. The chemoluminescence (chemiluminescence) of the differently prepared films was investi...

JA - Elektronika a optoelektronika, elektrotechnika

  • 2014
    • •
  • Jx
    • •
  • Link
Result

Prospective study of mutations in EGFR signal pathway in correlation with cetuximab therapy

Prospective study of mutations in EGFR signal pathway in correlation with cetuximab therapy is about our own results (grant project)......

FD - Onkologie a hematologie

  • 2011
    • •
  • O
  • 1 - 10 out of 43 960