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102 (0,079s)

Result

In vitro susceptibility of adenovirus to antiviral drugs in species-dependent

In vitro susceptibility of adenovirus to antiviral drugs in species-dependent...

FD - Onkologie a hematologie

  • 2005
  • Jx
Result

Detection and quantification of human adenovirus serotype 40 and 41 using methods qPCR

Aim of the methodology is rapid detection and quantification of human adenovirus. The system was designed to detect all serotypes of adenovirus serotypes focusing on AdV40 and AdV41 and was useful for diagnosis in humans....

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2015
  • NmetC
  • Link
Result

In vitro susceptibility of adenovirus to antiviral drugs is species-dependent.

In the present study, in vitro susceptibility of adenovirus infections to the antiviral drugs cidofovir and ribavirin was evaluated.

FD - Onkologie a hematologie

  • 2005
  • Jx
Result

Passive tumour targeting of polymer-coated adenovirus for cancer gene therapy

Adenovirus provides many opportunities as a vector for delivery of cytotoxic genes to tumours. Polymer coating of adenovirus is known to increase its plasma circulation kinetics, affording the possibility of active and passive targe...

CD - Makromolekulární chemie

  • 2007
  • Jx
Result

Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus

Systemic delivery of adenoviral vectors is a major goal in cancer gene therapy. Surface-masking technique based on multivalent HPMA copolymers was used to ablate all pathways of receptor-mediated infection. Polymer coating of adenovirus gave...

CC - Organická chemie

  • 2004
  • Jx
Result

Adenovirus type 5 (Ad5) is sequestered and inactivated by binding to coxsackievirus and adenovirus receptor (CAR) and complement receptor 1 (CR1) on human erythrocytes

Human erythrocytes presents Coxsackie virus-adenovirus receptor providing an Ad5 sequestration mechanism that protects them against systemic virus infection but a virus binds via the fiber protein of Ad5 leading to close juxtaposition with t...

CD - Makromolekulární chemie

  • 2008
  • D
Result

Adenovirus retargeting and systemic delivery.

Surface modification of adenovirus with multivalent HPMA copolymers gives dense virus coating and endows the virus with protection against anti-virus antibodies. It also provides a simple means to link potential retargeting agents (growth fa...

CC - Organická chemie

  • 2003
  • C
Result

Adenovirus-mediated gene transfer of vil-10 in experimental corneal transplantation

Corneal transplantation...

FF - ORL, oftalmologie, stomatologie

  • 2002
  • C
Result

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1

adenovirus pathology. Here we define the mechanism of Ad5 binding to human erythrocytes and document presentation of Coxsackie virus-adenovirus receptor (CAR) and complement......

CD - Makromolekulární chemie

  • 2009
  • Jx
Result

Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor

Normal virus tropism can be ablated by physically shielding the virus surface with reactive hydrophilic polymers and that linkage of novel ligands enables virus retargeting through chosen receptors. The resulting mEGF-polymer coated adenovirus

CD - Makromolekulární chemie

  • 2008
  • Jx
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