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1 413 (0,503s)

Result

Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases

as the TCR repertoire, is characterised by enormous diversity and inter-individual of specific clonotypes in the TCR repertoire of IBD patients, and particularly in patients identified TCR repertoire<...

Gastroenterology and hepatology

  • 2020
  • Jimp
  • Link
Result

Mother and child T cell receptor repertoires: deep profiling study

profiling of T cell receptor (TCR) repertoires for peripheral blood samples of three 5 105 to 2 106 TCR beta clonotypes per individual. We performed comparative analysis of these TCR repertoires with the ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013
  • Jx
  • Link
Result

Repertoire analysis of γδ T cells in the chicken enables functional annotation of the genomic region revealing highly variable pan-tissue TCR gamma V gene usage as well as identifying public

. The TCR repertoire defines different subsets of γδ T cells, and such analysis is facilitated by well-annotated TCR loci. γδ T cells are considered at the cusp of innate understanding of TCR repertoire bi...

Veterinary science

  • 2021
  • Jimp
  • Link
Result

Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians

The diversity, architecture, and dynamics of the TCR repertoire largely characterize the extremes of lifelong TCR repertoire evolution, analyzing samples ranging TCR repertoire, albeit structurall...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2016
  • Jx
  • Link
Result

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

behind, owing to the enormous diversity of the TCR repertoire and the scarcity that VDJdb is a versatile instrument for the annotation of TCR repertoire data, enabling of rearranged T-cell receptor (TCR) ...

Immunology

  • 2018
  • Jimp
  • Link
Result

Comparative analysis of murine T-cell receptor repertoires

profiling of T-cell receptor (TCR) repertoires becomes a powerful tool. The structure of TCR repertoires is instructive even before the antigen specificity of each approaches for the comparative analysis of murine...

Immunology

  • 2018
  • Jimp
  • Link
Result

VDJtools: Unifying post-analysis of T cell receptor repertoires

of T cell receptor (TCR) repertoires post-analysis tasks, provides a detailedDespite the growing number of immune repertoire sequencing studies, the field still lacks software for analysis and comprehension of this high-di...

CE - Biochemie

  • 2015
  • Jx
  • Link
Result

Method for identification of condition associated public antigen receptor sequences

Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to per...

Immunology

  • 2018
  • Jimp
  • Link
Result

Preparing unbiased T cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling

High throughput sequencing has the power to reveal the nature of adaptive immunity as represented by the full complexity of T cell receptor (TCR) and antibody (IG) repertoires, but is at present severely compromised by the quantitat...

EB - Genetika a molekulární biologie

  • 2013
  • Jx
  • Link
Result

Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

on MHC II. However, it remains largely unknown whether distinct or shared repertoires of Treg TCRs are mobilized in response to different challenges in the same tissue or the same challenge in different tissues. Here we use a fixed...

Biological sciences

  • 2024
  • Jimp
  • Link
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