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Pentylentetrazol Associated Changes of Hippocampal Neurons in Immature Rats
Neurodegeneration of the hippocampus after pentylentetrazol...
ED - Fyziologie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
A single episode of neonatal seizures alters the cerebellum of immature rats
Single pentylentetrazol induced seizures in rat pups reduced proliferation of immature cells and damaged more differentiated Purkinje cells of the cerebellum. Immucytochemistry showed increased GluR2/3 in Purknje cells and GLT1 in the surrou...
FH - Neurologie, neurochirurgie, neurovědy
- 2011 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Increased susceptibility to pentetrazol-induced seizures in developing rats after cortical photothrombotic ischemic stroke at P7
The present paper describes changes in seizure susceptibility after cortical photothrombotic ischemic lesion induced in 7 days old rats. Cortical ischemic lesion during early development affected differently the susceptibility of rat?s brain to three...
FH - Neurologie, neurochirurgie, neurovědy
- 2013 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Partial agonist of benzodiazepine receptors Ro 19-2088 elicits withdrawal symptoms after short-term administration in immature rats
Immature brain is more prone than mature one to develop withdrawal symptoms after short term administration of partial agonists of benzodiazepine receptors. Even 5-day-administration elicits increase of seizure susceptibility in P12 rats. Whether hig...
FH - Neurologie, neurochirurgie, neurovědy
- 2012 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Perampanel exhibits anticonvulsant action against pentylentetrazol-induced seizures in immature rats
Perampanel is a new antiepileptic drug with unique mechanism of action - antagonism of AMPA receptors. Its action in immature animals is not yet sufficiently known therefore we started to study anticonvulsant action of perampanel pretreatment (1-20 m...
Neurosciences (including psychophysiology)
- 2021 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats
In spite of use of cannabidiol (CBD), a non-psychoactive cannabinoid, in pediatric patients with epilepsy, preclinical studies on its effects in immature animals are very limited. In the present study we investigated anti-seizure activity of CBD (10 ...
Pharmacology and pharmacy
- 2022 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Anticonvulsive effects and pharmacokinetic profile of cannabidiol (Cbd) in the pentylenetetrazol (ptz) or n‐methyl‐d‐aspartate (nmda) models of seizures in infantile rats
In spite of use of cannabidiol (CBD), a non-psychoactive cannabinoid, in pediatric patients with epilepsy, preclinical studies on its effects in immature animals are very limited. In the present study we investigated anti-seizure activity of CBD (10 ...
Pharmacology and pharmacy
- 2022 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
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