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Insulin-like growth factor I (IGF-I) and long R(3) IGF-I differently affect development and messenger ribonucleic acid abundance for IGF-binding proteins and type IIGF receptors in in vitro produced
Insulin-like growth factor I and long R(3)IGF-I differently affect development and messenger ribonucleic acid abundance for IGF-binding proteins and type IIGF receptors in in vitro produced bovine embryos....
EB - Genetika a molekulární biologie
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
The role of transforming growth factor beta signaling in cancer.
Mutations in type I and II transforming growth factor beta receptors genes and in genes for Smad proteinsdominate to the loss of the cells sensitivity to the antiproliferative effect of transforming growth factor b...
FD - Onkologie a hematologie
- 2002 •
- Jx
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain
growth factors (IGF)-I/II are major growth factors. Insulin and IGFs cross-bind with different affinities to closely related insulin receptor isoforms A and B (IR-A and IR-B) and insulin-like growth factor
CE - Biochemie
- 2016 •
- Jx •
- Link
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Insulin-like Growth Factors in a clinical setting: Review of IGF-I
commonly konwn is Insulin-Like Growth Factor I (IGF-I). Despite considerable current knowledge of IGF-I, however, its bioaktivity is incompletely understood. Measurement of IGF-I is of the utmost importan...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2015 •
- Jx •
- Link
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Signal pathway induced by cytokines of the transforming growth factor beta (TGFß) family.
The transforming growth factor beta (TGFß) family members, including TGFßs proper, activins and bone morphogenetic proteins (BMPs), bind to specific serine/ threonine kinase receptors and transmit intracellular signals through Smad ...
FD - Onkologie a hematologie
- 2002 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Insulin-Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity
, and that the D-I domain Pro-Leu-Lys residues are important factors for a different IRA versusInsulin, insulin-like growth factors 1 and 2 (IGF-1 and -2, respectively), and their receptors (IR and IGF-1R) are the ...
CE - Biochemie
- 2016 •
- Jx •
- Link
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Complex I and the sAMP Cascade in Human Physiopathology
In mammalian cells the cAMP cascade regulates general and specialized functions in response to the binding of hormones, neurotransmitters, growth factors and cytokines to plasma membrane receptors....
EE - Mikrobiologie, virologie
- 2002 •
- Jx
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
A comparison of in vitro methods for determining the membrane receptor expression in cell lines
Introduction: Determining the number of expressed receptors per cell (NRPC method. These two methods, both based on radiolabeled ligand-receptor binding, were compared with the data on receptor expression found using quanti...
FR - Farmakologie a lékárnická chemie
- 2012 •
- Jx •
- Link
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Tumour necrosis factor-alpha soluble receptors type I are related to symptoms and left ventricular function in hypertrophic cardiomyopathy
High circulating levels of tumour necrosis factor-alpha (TNF-alpha) and its soluble receptors (sTNFRI, sTNFRII) are involved in the pathogenesis of congestive heart failure due to left ventricular (LV) systolic dysfunction. However,...
FA - Kardiovaskulární nemoci včetně kardiochirurgie
- 2001 •
- Jx
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Gefitinib Induces Epidermal Growth Factor Receptor Dimers Which Alters the Interaction Characteristics with (125)I-EGF
The tyrosine kinase inhibitor gefitinib inhibits growth in some tumor types by targeting the epidermal growth factor receptor (EGFR). Previous studies show that the affinity of the EGF-EGFR interaction varies between hosting cell li...
FR - Farmakologie a lékárnická chemie
- 2011 •
- Jx •
- Link
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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