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8 247 (0,076s)

Result

Clinical Manifestations and Results of Laboratory Examinations in Four Patients with Alpha-Mannosidosis

Alpha-Mannosidosis. Clinical Manifestations and Results of Laboratory...

FG - Pediatrie

  • 2008
  • Jx
Result

Natural history of alpha mannosidosis a longitudinal study

Background: Alpha-Mannosidosis is a rare lysosomal storage disorder, caused by the deficiency of the enzyme alpha-Mannosidase. Clinically it is characterized by hearing: In this multicenter longitudinal study clinical data ...

EB - Genetika a molekulární biologie

  • 2013
  • Jx
  • Link
Result

Ultrastructural and functional abnormalities of mitochondria in cultivated fibroblasts from alpha-mannosidosis patients

Mannosidosis -alpha is a lysosomal storage disorder caused by ?-mannosidase deficiency. Clinical course of the disease ranges from severe infantile to milder juvenile type and includes mental retardation, skeletal deformities, coars...

EA - Morfologické obory a cytologie

  • 2009
  • Jx
Result

White matter alteration and cerebellar atrophy are hallmarks of brain MRI in alpha-mannosidosis

Objective: Despite profound neurological symptomatology there are only few MRI studies focused on the brain abnormalities in alpha-mannosidosis (AM). Our aim was to characterize brain MRI findings in a large cohort of AM patients al...

Endocrinology and metabolism (including diabetes, hormones)

  • 2021
  • Jimp
  • Link
Result

Variant c.2158-2A>G in MANBA is an important and frequent cause of hereditary hearing loss and beta-mannosidosis among the Czech and Slovak Roma population- evidence for a new ethnic-specific variant

-mannosidosis whose clinical manifestation includes deafness and mental retardation. Since 1986, only 23 patients with beta-mannosidosis and biallelic MANBA variants have been described worldwide. RESULTS: We now report on further 1...

Neurosciences (including psychophysiology)

  • 2020
  • Jimp
  • Link
Result

Monitoring and integrated care coordination of patients with alpha-mannosidosis: A global Delphi consensus study

Introduction: Current literature lacks consensus on initial assessments and routine follow-up care of patients with alpha-mannosidosis (AM). A Delphi panel was conducted to generate and validate recommendations on best practices for...

Paediatrics

  • 2024
  • Jimp
  • Link
Result

Ultrastructural and functional abnormalities of mitochondria in cultivated fibroblasts from ? -mannosidosis patiens

Alfa-Mannosidosis is a lysosomal storage disorder caused by alfa-mannosidase defficiency. The aim of the study was to analyse mitochondrial ultrastructure and function in cultivated fibroblasts from three pacients with alfa-mannosidase. In a...

ED - Fyziologie

  • 2009
  • Jx
Result

Inhibition of alpha-amylase and alpha-glucosidase with natural substances

Review of natural compounds with inhibition activity on alpha-amylase and alpha-glucosidase and with possible usage in diagnosis and treatment of diabetes and obesity....

FR - Farmakologie a lékárnická chemie

  • 2009
  • Jx
Result

Stereoselective Synthesis of (E)-alpha-Fluorovinylphosphonates from alpha,alpha-Difluorophosphonates

alpha,alpha-Difluorophosphonates, which are readily available from alkyl halides and diethyl difluoromethylphosphonate, undergo elimination of hydrogen fluoride using alkali metal alkoxides to provide alpha-fluorovinylphosp...

CC - Organická chemie

  • 2011
  • Jx
  • Link
Result

Water quality - Determination of gross alpha activity

The standard is applicable for determination of gross alpha in waters. The standard states two methods. Gross alpha determination is not an absolute determination of the sample alpha radioactive content, but a relative dete...

Nuclear physics

  • 2021
  • Hleg
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