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Metabolic profile of methylazoxymethanol model of schizophrenia in rats and effects of three antipsychotics in long-acting formulation
phenotype of a methylazoxymethanol (MAM) schizophrenia-like model together in the MAM rats. Further, the MAM model showed lower abdominal adiposity, while OLA increased it. Serum lipid p...
Pharmacology and pharmacy
- 2020 •
- Jimp •
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The brain changes of anisotropy in MAM model of schizophrenia in rat
Methylazoxymethanol acetate(MAM)-exposed rats were used to parallel neuropathological abnormalities seen in schizophrenia patients. Corpus callosum (cc aim was to confirm this model by DTI of white matter structure...
BH - Optika, masery a lasery
- 2013 •
- D
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D - Stať ve sborníku
Olanzapine, but not haloperidol, exerts pronounced acute metabolic effects in the methylazoxymethanol rat model
Our results demonstrate metabolic vulnerability in female prenatally MAM-exposed rats indicating that findings from healthy animals are likely to provide. In the context of metabolic disturbances, neurodevelopmental models ...
Pharmacology and pharmacy
- 2024 •
- Jimp •
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Reactivity to addictive drugs in the methylazoxymethanol (MAM) model of schizophrenia in male and female rats
of both sexes in a neurodevelopmental model of schizophrenia induced by prenatal methylazoxymethanol (MAM) acetate exposure. Methods: MAM (22 mg/kg) was administered data showed no effect of the MAM m...
Psychiatry
- 2017 •
- Jimp •
- Link
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Suppression of Methamphetamine Self-Administration by Ketamine Pre-treatment Is Absent in the Methylazoxymethanol (MAM) Rat Model of Schizophrenia
addiction in schizophrenia using the methylazoxymethanol (MAM) acetate rat model on operant IV methamphetamine (METH) self-administration. MAM was administered to the self-administration session. As docum...
Neurosciences (including psychophysiology)
- 2017 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue
adipose tissue of prenatally methylazoxymethanol (MAM) acetate exposed rats, a well and the antipsychotics treatment. MAM model was associated with the deregulation of the TOR (target animals. Treatments ...
Biochemistry and molecular biology
- 2021 •
- Jimp •
- Link
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The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology
-tetrahydrocannabinol (aTHC) may affect the impact of prenatal methylazoxymethanol acetate (MAM) or perinatal THC (pTHC) exposure in adult rats. We found that MAM and pTHC-exposed rats MAM or pTHC...
Pharmacology and pharmacy
- 2023 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology
methylazoxymethanol acetate (MAM) or perinatal THC (pTHC) exposure in adult rats. We found that MAM and pTHC-exposed rats, when compared to the control group (CNT), were expression in the prefrontal corte...
Biochemistry and molecular biology
- 2023 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin Labelling MRI in rats
BioSpec 94/30USR scanner) in rats. In this study, prenatal exposure to methylazoxymethanol acetate (MAM, 22 mg/kg) at gestational day (GD) 17 and the perinatal treatment with the neurodevelopmental hypothesis of schizophre...
Neurosciences (including psychophysiology)
- 2019 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin Labelling MRI in rat
BioSpec 94/30USR scanner) in rats. In this study, prenatal exposure to methylazoxymethanol acetate (MAM, 22 mg/kg) at gestational day (GD) 17 and the perinatal treatment with the neurodevelopmental hypothesis of schizophre...
Neurosciences (including psychophysiology)
- 2019 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
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