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Intranuclear sphingomyelin is associated with transcriptionally active chromatin and plays a role in nuclear integrity
In cooperation with the University in Lausanne, ultrastructural study supported by biochemical analysis revealed that phospholipid sphingomyellin plays an important role in synthetic processes taking place in cell nucleus. Apart form that, sphingomye...
EA - Morfologické obory a cytologie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Altered Plasma, Urine, and Tiissue Profiles of Sulfatides and Sphingomyelins in Patients with Renal Cell Carcinoma
in concentrations of sulfatides and sphingomyelins in plasma and urine in RCC patients compared gradual changes in sulfatide and sphingomyelin concentrations with increasing tumor......
Biochemistry and molecular biology
- 2022 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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Behavior of sphingomyelin and ceramide in a tear film lipid layer model
polar lipid components of the tear film lipid later: sphingomyelin and ceramide lipids in a tear film lipid layer model. Sphingomyelin headgroups are significantly......
Physical chemistry
- 2017 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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GM1 Ganglioside Inhibits β-Amyloid Oligomerization Induced by Sphingomyelin
Beta-Amyloid (Aβ) oligomers are neurotoxic and implicated in Alzheimer's disease. Neuronal plasma membranes may mediate formation of Aβ oligomers in vivo. Membrane components sphingomyelin and GM1 have been shown to promote aggregation of Aβ...
CF - Fyzikální chemie a teoretická chemie
- 2016 •
- Jx •
- Link
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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Diffusion of sphingomyelin and myelin oligodendrocyte glycoprotein in the membrane of OLN-93 oligodendroglial cells studied by fluorescence correlation spectroscopy
sphingomyelin (Bodipy FL-C5 SM). The protein was the myelin oligodendrocyte glycoprotein...
CF - Fyzikální chemie a teoretická chemie
- 2005 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Sphingomyelin and phosphatidylcholine contrarily affect the induction of apoptosis in intestinal epithelial cells
The major alimentary sources for the plasma membrane lipid sphingomyelin (SM) are dairy products, eggs, and meat.We recently reported that the SM metabolite ceramide induces cathepsin D mediated apoptosis in murine intestinal epithelial cell...
ED - Fyziologie
- 2014 •
- Jx •
- Link
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Effects of sphingomyelin/ceramide ratio on the permeability and microstructure of model stratum corneum lipid membranes
The conversion of sphingomyelin (SM) to a ceramide (Cer) by acid sphingomyelinase (aSMase) is an important event in skin barrier development A deficiency in aSMase in diseases such as Niemann Pick disease and atopic dermatitis coincides with...
FR - Farmakologie a lékárnická chemie
- 2014 •
- Jx •
- Link
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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Physiologically-relevant levels of sphingomyelin, but not GM1, induces a beta-sheet-rich structure in the amyloid-beta(1-42) monomer
of sphingomyelin (SM) (30% SM, 40% POPC, and 30% cholesterol), and the GM1 ganglioside (5% GM1 of A beta 42 in the sphingomyelin-enriched bilayer most resembles beta-sheet-rich......
Biochemistry and molecular biology
- 2018 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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SMPD1 variants do not have a major role in rapid eye movement sleep behavior disorder
Mutations in the sphingomyelin phosphodiesterase 1 (SMPD1) gene were reported to be associated with Parkinson's disease and dementia with Lewy bodies. In the current study, we aimed to evaluate the role of SMPD1 variants in isolated rap...
Neurosciences (including psychophysiology)
- 2020 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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(GM1) Ganglioside Inhibits beta-Amyloid Oligomerization Induced bySphingomyelin
beta-Amyloid (A beta) oligomers are neurotoxic and implicated in Alzheimer's disease. Neuronal plasma membranes may mediate formation of A beta oligomers in vivo. Membrane components sphingomyelin and GM(1) have been shown to promote aggrega...
CE - Biochemie
- 2016 •
- Jx •
- Link
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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