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6 (0,15s) •

Result

Expression patterns and prognostic relevance of subtype-specific transcription factors in surgically resected small-cell lung cancer: an international multicenter study

(ASCL1, NEUROD1, POU2F3, YAP1) present an evolving area of research in small-cell viability assays in 26 human SCLC cell lines. Besides SCLC-A (ASCL1-dominant), SCLC-AN (combined ASCL1/NEUROD1), SCLC-N (NEUROD1-dominant), ...

Pathology

  • 2022
    • •
  • Jimp
    • •
  • Link
Result

Small cell lung cancer - news in the tumour's biology

to the expression of transciptional factors ASCL1 (SCLC-A), NEUROD1 (SCLC-D), POU2F3 (SCLC-P...

Pathology

  • 2023
    • •
  • JSC
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  • Link
Result

ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance

of proneural marker ASCL1 (enriched in SHH-1B) and glial markers OLIG2 and GFAP (absent and age of onset (but not ASCL1 staining status) were independently associated......

Oncology

  • 2022
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  • Jimp
    • •
  • Link
Result

Whole Genome Microarray Analysis of Chicken Embryo Facial Prominences

The face is one of the three regions most frequently affected by congenital defects in humans. To understand the molecular mechanisms involved, it is necessary to have a more complete picture of gene expression in the embryo. Here, we use microarrays...

EB - Genetika a molekulární biologie

  • 2010
    • •
  • Jx
Result

Methylation status of selected genes in non-small cell lung carcinoma - current knowledge and future perspectives

profiles of TP53, RB1, KEAP1, and STK11 and expression patterns of ASCL1, DLL3...

Pathology

  • 2024
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  • Jimp
    • •
  • Link
Result

KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes

Transdifferentiation of fibroblasts into induced neuronal cells (iNs) by the neuron-specific transcription factors Brn2, Myt1l, and Ascl1 is a paradigmatic example of inter-lineage conversion across epigenetically distant cells. Despite trem...

Neurosciences (including psychophysiology)

  • 2018
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  • Jimp
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  • Link
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