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Results

15 206 results (1,055s) •

Result

DNA adducts in genotoxicology

DNA adducts are important marker indicating the initiation phase of mutagenesis and carcinogenesis...

CE - Biochemie

  • 2006
    • •
  • D
Result

Genotoxicity induced by xenobiotics:the role of DNA adducts, individual susceptibility and DNA repair.

Specific markers of DNA damage (DNA adducts) along with parameters of individual susceptibility and individual variability of DNA repair are inevitable in understanding genotoxic and/or carcinogenic effects of xeno...

FM - Hygiena

  • 2002
    • •
  • Jx
Result

Monitoring of DNA adducts in humans and P-32-postlabelling methods. A review

Method of P-32-postlabelling for DNA adduct formation monitoring...

CE - Biochemie

  • 2004
    • •
  • Jx
Result

Identification of 1-adenine DNA adducts in workers occupationally exposed to styrene.

The results show a potential of 1-adenine DNA adducts for predicting risks in the workers exposed to styrene.

EB - Genetika a molekulární biologie

  • 2001
    • •
  • Jx
Result

Ellipticine forms covalent DNA adducts in rats with properties similar to adducts formed in vitro after its activation by cytochromes P450 or peroxidases

Ellipticine forms covalent DNA adducts in rats with properties similar to adducts formed in vitro after its activation by cytochromes P450 or peroxidases......

CE - Biochemie

  • 2001
    • •
  • Jx
Result

Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the 32P-postlabeling technique

that in contrast to covalent DNA adducts formed by ellipticine, the adducts generated by formaldehyde-mediated covalent binding of doxorubicin to DNA are not detectable by the 32P-postlabeling assay. No DNA

CE - Biochemie

  • 2012
    • •
  • Jx
Result

Covalent DNA Adduct Formation Mediated by Cytochromes 450

Chapter describes the methodilogical details to detect the DNA adducts from drugs after their activation by cytochromes 450...

CE - Biochemie

  • 2004
    • •
  • C
Result

32P-Postlabeling Analysis of DNA Adducts

and quantitation of DNA adducts and covalent modifications of the DNA. It consists of four main steps: (1) enzymatic digestion of DNA to 3'-monophosphate nucleosides; (2) enrichmentof the adducts; (3) 5'O...

CE - Biochemie

  • 2013
    • •
  • C
    • •
  • Link
Result

ELISA-VIDITEST anti-BPDE-DNA Human kit for IgM antibodies detection to benzo(a)pyrene diolepoxide?DNA adducts in human serum.

Whereas the anti? benzo[a]pyrene diolepoxide?DNA (anti-BPDE-DNA) adduct antibodies were shown serve solely as a biomarker of the toxic effects of long-term PAH exposure. Higher antibodies titre of these antibodies were foun...

EB - Genetika a molekulární biologie

  • 2010
    • •
  • Gprot
Result

ELISA-VIDITEST anti-BPDE-DNA Mouse kit for IgG antibodies detection to benzo(a)pyrene diolepoxide?DNA adducts in mouse serum.

Whereas the anti? benzo[a]pyrene diolepoxide?DNA (anti-BPDE-DNA) adduct antibodies were shown serve solely as a biomarker of the toxic effects of long-term PAH exposure. Higher antibodies titre of these antibodies were foun...

EB - Genetika a molekulární biologie

  • 2010
    • •
  • Gfunk
  • 1 - 10 out of 15 206