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DNA adducts in genotoxicology
DNA adducts are important marker indicating the initiation phase of mutagenesis and carcinogenesis...
CE - Biochemie
- 2006 •
- D
Rok uplatnění
D - Stať ve sborníku
Genotoxicity induced by xenobiotics:the role of DNA adducts, individual susceptibility and DNA repair.
Specific markers of DNA damage (DNA adducts) along with parameters of individual susceptibility and individual variability of DNA repair are inevitable in understanding genotoxic and/or carcinogenic effects of xeno...
FM - Hygiena
- 2002 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Monitoring of DNA adducts in humans and P-32-postlabelling methods. A review
Method of P-32-postlabelling for DNA adduct formation monitoring...
CE - Biochemie
- 2004 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Identification of 1-adenine DNA adducts in workers occupationally exposed to styrene.
The results show a potential of 1-adenine DNA adducts for predicting risks in the workers exposed to styrene.
EB - Genetika a molekulární biologie
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Ellipticine forms covalent DNA adducts in rats with properties similar to adducts formed in vitro after its activation by cytochromes P450 or peroxidases
Ellipticine forms covalent DNA adducts in rats with properties similar to adducts formed in vitro after its activation by cytochromes P450 or peroxidases......
CE - Biochemie
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the 32P-postlabeling technique
that in contrast to covalent DNA adducts formed by ellipticine, the adducts generated by formaldehyde-mediated covalent binding of doxorubicin to DNA are not detectable by the 32P-postlabeling assay. No DNA
CE - Biochemie
- 2012 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Covalent DNA Adduct Formation Mediated by Cytochromes 450
Chapter describes the methodilogical details to detect the DNA adducts from drugs after their activation by cytochromes 450...
CE - Biochemie
- 2004 •
- C
Rok uplatnění
C - Kapitola v odborné knize
32P-Postlabeling Analysis of DNA Adducts
and quantitation of DNA adducts and covalent modifications of the DNA. It consists of four main steps: (1) enzymatic digestion of DNA to 3'-monophosphate nucleosides; (2) enrichmentof the adducts; (3) 5'O...
CE - Biochemie
- 2013 •
- C •
- Link
Rok uplatnění
C - Kapitola v odborné knize
Výsledek na webu
ELISA-VIDITEST anti-BPDE-DNA Human kit for IgM antibodies detection to benzo(a)pyrene diolepoxide?DNA adducts in human serum.
Whereas the anti? benzo[a]pyrene diolepoxide?DNA (anti-BPDE-DNA) adduct antibodies were shown serve solely as a biomarker of the toxic effects of long-term PAH exposure. Higher antibodies titre of these antibodies were foun...
EB - Genetika a molekulární biologie
- 2010 •
- Gprot
Rok uplatnění
Gprot - Prototyp
ELISA-VIDITEST anti-BPDE-DNA Mouse kit for IgG antibodies detection to benzo(a)pyrene diolepoxide?DNA adducts in mouse serum.
Whereas the anti? benzo[a]pyrene diolepoxide?DNA (anti-BPDE-DNA) adduct antibodies were shown serve solely as a biomarker of the toxic effects of long-term PAH exposure. Higher antibodies titre of these antibodies were foun...
EB - Genetika a molekulární biologie
- 2010 •
- Gfunk
Rok uplatnění
Gfunk - Funkční vzorek
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