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205 (0,073s)

Result

CD36 mediates the phagocytosis of Plasmodium falciparuminfected erythrocytes by rodent macrophages

Using macrophages from CD36 wild-type (WT), CD36-null, and CD36 transgenically-rescued rodents, we demonstrate a major role for CD36 in the phagocytosis of Plasmodium falciparum-parasitized erythrocytes......

EB - Genetika a molekulární biologie

  • 2004
  • Jx
Result

Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine

Hypoxanthine-guanine-(xanthine) phosphoribosyltransferase catalyses the synthesis of the purine nucleoside monophosphates essential for DNA/RNA production in protozoan parasites. Acyclic nucleoside phosphonates have been found to inhibit Plasmodi...

CC - Organická chemie

  • 2012
  • Jx
  • Link
Result

An Epithelial Serine Protease, AgESP, Is Required for Plasmodium Invasion in the Mosquito Anopheles gambiae

epithelial serine protease (AgESP) as critical for Plasmodium parasites to cross these two epithelial barriers. AgESP silencing greatly reduces Plasmodium berghei and Plasmodium falciparum midgut invasion. AgESP e...

EB - Genetika a molekulární biologie

  • 2012
  • Jx
  • Link
Result

Diagnosis, treatment and prophylaxis of malaria in the Czech Republic

clinical presentation. The most severe forms of malaria are caused by Plasmodium falciparum. The diagnosis of malaria is based on examination of stained thick and thin blood smears. This method enables determination of Plasmodi...

Infectious Diseases

  • 2018
  • JSC
  • Link
Result

Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates.

Annotation not available...

CE - Biochemie

  • 1999
  • Jx
Result

Diagnosis, treatment and prophylaxis of malaria

clinical presentation. The most severe forms of malaria are caused by Plasmodium falciparum. The diagnosis of malaria is based on examination of stained thick and thin blood smears. This method enables determination of Plasmodi...

Infectious Diseases

  • 2018
  • Jost
Result

Ecology of malaria infections in western lowland gorillas/ninhabiting Dzanga Sangha Protected Areas, Central African/nRepublic

of Plasmodium, including the predecessor of Plasmodium falciparum. Little is known about of Plasmodium species. The effects of sex and age as factors influencing levels of infection with Plasmodium in hab...

EB - Genetika a molekulární biologie

  • 2015
  • Jx
  • Link
Result

Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors

nanomolar in vitro potency for blood-stage Plasmodium falciparum and low cytotoxicity for erythrocytic-stage P. falciparum over HepG2 and H460 cells, which is largely driven P. falciparum cell extracts and determi...

Biochemistry and molecular biology

  • 2023
  • Jimp
  • Link
Result

Diagnosis, treatment and prophylaxis of malaria in the Czech Republic

clinical presentation. The most severe forms of malaria are caused by Plasmodium falciparum. The diagnosis of malaria is based on examination of stained thick and thin blood smears. This method enables determination of Plasmodi...

Infectious Diseases

  • 2018
  • JSC
Result

N2'-Branched Acyclic Nucleoside Phosphonates Containing 9-Deazahypoxanthine as Inhibitors of Plasmodium falciparum 6-Oxopurine Phosphoribosyltransferase

Twelve N2'-branched acyclic nucleoside phosphonates and bisphosphonates were synthesized as potential inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPRT), the key enzyme in the puri...

Organic chemistry

  • 2023
  • Jimp
  • Link
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