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Efficient gene targeting of the Rosa26 locus in mouse zygotes using TALE nucleases
targeting ofthe mouse Rosa26 locus by transcription activator-like effector nucleases TurboRFP and TagBFP fluorescent proteins into the first intron of the Rosa26 gene, and in this way generated two transgenic mice. We als...
EB - Genetika a molekulární biologie
- 2014 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Novel TALEN-generated mCitrine-FANCD2 fusion reporter mouse model for in vivo research of DNA damage response
of the reporter gene under controlled conditions, whether in a specific locus in the genome or in a 'safe harbor' locus. Historically, the ROSA26 locus is used for gene knock......
Biochemistry and molecular biology
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Rosa26-p16-LuctdT reporter mouse line
DNA damage caused by irradiation, chemical substances and different metabolites often leads to irreversible mutations influencing human health. The aim of the project is to develop and apply more sensitive methods enabling detection and study of DNA ...
EB - Genetika a molekulární biologie
- 2015 •
- Gfunk
Rok uplatnění
Gfunk - Funkční vzorek
2al-Rosa26-p16-LuctdT reporter mouse line
DNA damage caused by irradiation, chemical substances and different metabolites often leads to irreversible mutations influencing human health. The aim of the project is to develop and apply more sensitive methods enabling detection and study of DNA ...
EB - Genetika a molekulární biologie
- 2015 •
- Gfunk
Rok uplatnění
Gfunk - Funkční vzorek
Homing of lin-/CD117+ hematopoietic stem cells
In this report, we describe the homing of hematopoietic stem cells (HSCs) to non-hematopoietic tissues in lethally irradiated (9 Gy) hybrid mice transplanted intravenously with lin-/CD117+ bone marrow cells from ROSA26 mice. Hematopoietic st...
FD - Onkologie a hematologie
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Locus Computation in Dynamic Geometry Environment
to determine an unknown locus and its equation in terms of given properties using GeoGebra commands Locus and LocusEquation. After the use of these commands we present how computer arrives at the searched locus and how to ...
Education, special (to gifted persons, those with learning disabilities)
- 2019 •
- JSC •
- Link
Rok uplatnění
JSC - Článek v periodiku v databázi SCOPUS
Výsledek na webu
Locus computation in dynamic geometry environment
to determine an unknown locus and its equation in terms of given properties using GeoGebra commands Locus and LocusEquation. After the use of these commands we present how computer arrives at the searched locus and how to ...
Applied mathematics
- 2018 •
- JSC •
- Link
Rok uplatnění
JSC - Článek v periodiku v databázi SCOPUS
Výsledek na webu
Chord of conics
The paper deals with locus of points related to chords of conic sections. Firstly the locus is explored using dynamic geometry software GeoGebra, secondly using computer algebra system CoCoA by elimination the locus equatio...
Applied mathematics
- 2021 •
- Jost
Rok uplatnění
Jost - Ostatní články v recenzovaných periodicích
On One Locus in the Plane
In this work we deal with the problem: determine the locus of the point P such that the feet of the perpendiculars from P to (extended) sides of a given planar quadrilateral ABCD are concyclic. In general the locus is a cubic curve....
Applied mathematics
- 2019 •
- D •
- Link
Rok uplatnění
D - Stať ve sborníku
Výsledek na webu
On the locus related to chords of conic sections
The paper deals with the locus of points related to chords of conic sections. Firstly the locus is explored using dynamic geometry software, particularly for displaying it, secondly, using elimination in computer algebra software, t...
Education, general; including training, pedagogy, didactics [and education systems]
- 2021 •
- D
Rok uplatnění
D - Stať ve sborníku
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