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Result

VEGF-D Is the Strongest Angiogenic and Lymphangiogenic Effector Among VEGFs Delivered Into Skeletal Muscle via Adenoviruses

vascular endothelial growth factor (VEGF) family members VEGF-A, VEGF-B, VEGF-C, and VEGF-Das well as a VEGFR-3-specific mutant (VEGF-C156S) using adenoviral gene, angiogenesis and lymphangiogene...

FP - Ostatní lékařské obory

  • 2003
  • Jx
Result

Anti-VEGF agents

Molecule VEGF A plays a crucial role in the pathophysiology and development of neovascular membranes, and increased vascular permeability. VEGF is the lone player in this field, but his role is crucial. VEGF A is present in...

FF - ORL, oftalmologie, stomatologie

  • 2011
  • C
Result

Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial Tissue

of the VEGF family in vivo using adenoviral gene transfer. Adenoviruses (1*109 plaque-forming units [pfu]) encoding for VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-CN C and VEGF-D formation was...

FP - Ostatní lékařské obory

  • 2003
  • Jx
Result

Results of the intravitreal anti-VEGF in the therapy of ROP

Anti-VEGF therapy has been used in the treatment of ROP at our clinic since 2009. Macugen and Abastin are used.

FF - ORL, oftalmologie, stomatologie

  • 2015
  • O
Result

From SARS-CoV-2 to analgesia: harnessing the VEGF-A/NRP-1 axis for pain therapy

Vascular endothelial growth factor (VEGF) encompasses a family of secreted and development. The VEGF family consists of 5 members with VEGF-A being by far the most widely studied. VEGF-A signals though 2 different ...

Neurosciences (including psychophysiology)

  • 2023
  • O
  • Link
Result

Development of a nanomedicine-loaded hydrogel for sustained delivery of an angiogenic growth factor to the ischaemic myocardium

Growth Factor (VEGF) is complexed electrostatically with star-shaped or linear polyglutamic acid (PGA) polypeptides. Optimised PGA-VEGF nanomedicines provide VEGF encapsulation of > 99% and facilitate sustained release of ...

Other biological topics

  • 2019
  • Jimp
  • Link
Result

Translational Studies on the Potential of a VEGF Nanoparticle-Loaded Hyaluronic Acid Hydrogel

-in-gel delivery system for vascular endothelial growth factor (VEGF), composed of star-shaped polyglutamic acid-VEGF nanoparticles in a tyramine-modified hyaluronic acid hydrogel (nano-VEGF-HA-TA), is investigated. The abi...

Pharmacology and pharmacy

  • 2021
  • Jimp
  • Link
Result

Proteinuria and Hypertension in Patients Treated with Inhibitors of the VEGF Signalling Pathway - Incidence, Mechanisms and Management

Anti-VEGF therapy dramatically improved the outcome of patients with renal and hypertension. VEGF is indispensable for the normal development of glomerulus patientsbefore starting anti-VEGF therapy and regularly monitored d...

FD - Onkologie a hematologie

  • 2013
  • Jx
  • Link
Result

Enhanced Mitogenic Activity of Recombinant Human Vascular Endothelial Growth Factor VEGF(121) Expressed in E. coli Origami B (DE3) with Molecular Chaperones

We describe the production of a highly-active mutant VEGF variant, alpha(2)-PI1-8-VEGF(121), which contains a substrate sequence for factor XIIIa at the aminoterminus designed for incorporation into a fibrin gel. The alpha(2)-PI1-8-...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2016
  • Jx
  • Link
Result

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

Although vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) is traditionally regarded as an endothelial cell protein, evidence suggests that VEGFRs may characterized by florid vascularization and aberrantly elevated VEGF....

FD - Onkologie a hematologie

  • 2012
  • Jx
  • Link
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