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36 (0,136s)

Result

G-CSF plus azacitidine versus azacitidine alone for patients with high-risk myelodysplastic syndrome: academic, open label, randomized trial

Academic, open label, randomized trial: G-CSF plus azacitidine versus azacitidine alone for patients with high-risk myelodysplastic syndrome. GA trial is registered under EudraCT#: 2013-001639-38....

Hematology

  • 2022
  • Jimp
  • Link
Result

Evaluation of minimal residual disease in patients with De Novo acute myeloid leukemia treated with Azacitidine and Venetoclax combination therapy.

Evaluation of minimal residual disease in patients with De Novo acute myeloid leukemia treated with Azacitidine and Venetoclax combination therapy - conference abstract....

Hematology

  • 2023
  • O
Result

Sequences for determination of the transcription activity and expression levels of the target gene for 5-azacitidine treatment

Oligonucleotide sequences, designed to measure the relationship between abundance and localization of key molecular factors in samples of tumor cells towards improvement of the diagnosis, prognosis and estimate the potential effectiveness of treatmen...

EB - Genetika a molekulární biologie

  • 2012
  • Fuzit
  • Link
Result

Azacitidine and venetoclax in previously untreated acute myeloid leukemia

prognosis, even after treatment with a hypomethylating agent. Azacitidine added of age or older, or both to azacitidine plus either venetoclax or placebo. All patients received a standard dose of azacitidine (75 mg per squ...

Hematology

  • 2020
  • Jimp
  • Link
Result

Report of University Hospital Ostrava to the clinical trial protokol No: 2014-3634

Randomized, Two-Way, Crossover Study to Assess the Comparative Bioavailability of Subcutaneous Azacitidine Compared With Subcutaneous Vidaza® in Patients With Myelodysplastic Syndrome (MDS) on Azacitidine Therapy....

FD - Onkologie a hematologie

  • 2016
  • Vsouhrn
Result

Report from the latest analyzes of Vidaza (azacitidine) and Revlimid (lenalidomide) therapy in patients with myelodysplastic syndrome in the Czech Republic: data from MyDyS registry

This paper deals with recent analyzes of Vidaza (azacitidine) and Revlimid (lenalidomide) therapy in patients with myelodysplastic syndrome in the Czech Republic using data from MyDyS registry......

Hematology

  • 2019
  • Jost
  • Link
Result

Research Report University Hospital clinical trial AZA-MDS-003

A Phase 3, Multicenter, Randomized, Double-blind Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo Plus Best Supportive Care in Subjects With Red Blood Cell Transfusion-dependent Anemia and...

FD - Onkologie a hematologie

  • 2014
  • Vsouhrn
Result

Up-regulation of ribosomal genes is associated with a poor response to azacitidine in myelodysplasia and related neoplasms

Azacitidine (AZA) is a hypomethylating drug used to treat disorders associated with myelodysplasia and related neoplasms. Our data indicate that AZA treatment failure is associated with the up-regulation of ribosomal genes/pathways that are ...

FD - Onkologie a hematologie

  • 2016
  • Jx
  • Link
Result

Design of the VIALE-M phase III trial of venetoclax and oral azacitidine maintenance therapy in acute myeloid leukemia

with azacitidine, it leads to prolonged overall survival and rapid, durable remissions in combination with oral azacitidine (CC-486) as maintenance therapy in patients in complete......

Oncology

  • 2022
  • Jimp
  • Link
Result

5-Azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU.1 gene and cell differentiation capacity

Epigenetic 5-azacitidine (AZA) therapy of high-risk myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML) represents a promising, albeit not fully understood, approach. Hematopoietic transcription factor PU.1 is dynamically re...

FD - Onkologie a hematologie

  • 2012
  • Jx
  • Link
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