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Use of isotope labelling in mass spectrometry
Contribution summarises the use of isotope labelling in mass spectrometry.
CB - Analytická chemie, separace
- 2005 •
- D
Rok uplatnění
D - Stať ve sborníku
Multicomponent Reactions: A Promising Approach to Isotope Labeling
Isotopic labeling is an attractive modality that has been widely used in many development of isotopically labeled molecules has led to an increased demand for new isotopic labeling chemical method...
Organic chemistry
- 2024 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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13th International Symposium on the Synthesis and Applications of Isotopically Labelled Compounds
between experts in the field of application of isotopically labelled compounds in the basic and applied research with the emphasis on the life sciences. Isotopically labelled compounds are indispensable tools for ...
Organic chemistry
- 2018 •
- M
Rok uplatnění
M - Uspořádání konference
Analysis of IgG Fc-glycosylation using glycopeptide stable isotope labeling
For the first time, stable isotope labeling of the glycopeptide was used for IgG N-glycosylation analysis. Succinic anhydride was found as a suitable label protocol consisting of an in-solution tryptic digestion, a žone-pot...
CB - Analytická chemie, separace
- 2015 •
- O
Rok uplatnění
O - Ostatní výsledky
A Cost-effective Amino-acid-type Selective Isotope Labeling of Proteins Expressed in Leishmania tarentolae
We report a cost efficient approach for amino-acid-type selective isotope labeling of proteins expressed in Leishmania tarentolae. The method provides an economically advantageous alternative to recently established protocol for
EB - Genetika a molekulární biologie
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Synthesis of [13C6]-ibrutinib
Convenient and straightforward synthesis of ibrutinib labeled by carbon-13 isotope is reported. Isotopically labeled building block is introduced in the last step of reaction sequence affording sufficient isolated ...
Analytical chemistry
- 2021 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
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Isotopically labeled peptides provide site-resolved structural data with infrared spectra. Probing the structural limit of optical spectroscopy
Isotopic labeling, here exemplified by 13C substitution on the amide C=O group, can allow site-specific determination of peptide conformation with IR. Examples of helix and sheet (beta-hairpin) structures are reviewed....
CC - Organická chemie
- 2005 •
- D
Rok uplatnění
D - Stať ve sborníku
Synthetic study in the oxytocin field.
Isotopically labeled oxytocin with 13 C and 15 N in the C-terminal tripeptide part exhibited identical biological activity profile with the natural oxytocin....
CE - Biochemie
- 2001 •
- D
Rok uplatnění
D - Stať ve sborníku
Selective isotope labeling for NMR structure determination of proteins in complex with unlabeled ligands
are usually not available in an isotope-labeled form and NMR spectra may suffer from PEX19. The approach combines specific C-13, N-15 and H-2 isotope labeling with selective isotope-labeling and ...
Biochemistry and molecular biology
- 2019 •
- Jimp •
- Link
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Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Isotope exchange reactions of the hydrogen H-5 of selected pyrimidine derivatives and the preparation of tritium-labeled pyrimidines
The hydrogen-to-deuterium isotope exchange reaction of hydrogen in position 5 of pyrimidine derivatives was studied using NMR techniques. The dependence of the reaction rate on the pH and on the solvent composition was explored. In tracer ex...
CC - Organická chemie
- 2011 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
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