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60 (0,156s)

Result

Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms

by neurosteroids pregnanolone and pregnanolone sulfate and compare their mechanisms of action sulfate and pregnanolone potentiate glutamate release downstream of presynaptic Ca2 the effect of pregnanolone, but not...

Neurosciences (including psychophysiology)

  • 2021
  • Jimp
  • Link
Result

Pregnanolone isomers, pregnenolone and their polar conjugates around parturition.

The levels of four pregnanolone isomers and their polar conjugates and pregnenolone sulfate were measured in the plasma of using a simple quadrupole GC/MS system with electron impact ionization (pregnenolone isomers). RIA following HPLC sepa...

CC - Organická chemie

  • 2003
  • Jx
Result

Circulating levels of pregnanolone isomers during the third trimester of human pregnancy

Pregnanolone isomers during pregnancy...

FK - Gynekologie a porodnictví

  • 2007
  • Jx
Result

Sex - and age - related changes in epitestosterone in relation to pregnanolone sulfate and testosterone in normal subjects

Sex - and age - related changes in epitestosterone in relation to pregnanolone sulfate...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002
  • Jx
Result

Relationships of circulating pregnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy

Pregnanolone isomers and pregnancy...

FK - Gynekologie a porodnictví

  • 2007
  • Jx
Result

Neuroactive pregnanolone isomers during pregnancy

The pregnanolone isomers (PI) allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one), pregnanolone (3alpha-hydroxy-5beta-pregnan-20-one), isopregnanolone (3beta-hydroxy-5alpha-pregnan-20-one), epipregnanolone (3beta-hydroxy-5beta-p...

CC - Organická chemie

  • 2005
  • Jx
Result

Relationship of circulating pragnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy.

Pregnanolone isomers and their polar conjugates.

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2007
  • Jx
Result

Reinstatement of serum pregnanolone isomers and progesterone during alcohol detoxification therapy in premenopausal women

Serum allopregnanolone (3[alpha]-hydroxy-5[alpha]-pregnan-20-one; P3[alpha]5[alpha]), pregnanolone (P3[alpha]5[beta]), asopregnanolone (P3[beta]5[alpha]), epipregnanolone (P3[beta]5[beta], progesterone, pregnanolone sulfate (PregS),...

CC - Organická chemie

  • 2005
  • Jx
Result

Pregnanolone derivatives substituted in position 3 alpha, process for their preparation and use

In the present invention, there are disclosed pregnanolone derivative, a process for preparing pregnanolone derivatives of the general formula I in which Re1 is as indicated in the description, further the use of the pregnanolon...

CC - Organická chemie

  • 2012
  • P
  • Link
Result

Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age

Pregnanolone isomers (PI) are neuroinhibitors modulating GABAA receptors. In addition to the brain's in situ synthesis, some circulating steroids can penetrate the blood-brain barrier. To assess the physiological impact, PI and conjugates we...

CC - Organická chemie

  • 2006
  • Jx
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