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Heritability and tissue specificity of expression quantitative trait loci
We described the influence of heritability and allelic effect of the quantitative trait locus on detection of cis- and trans-acting eQTLs and discuss how these factors operate in a tissue-specific context......
EB - Genetika a molekulární biologie
- 2006 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Chromosomal Mapping of a Major Quantitative trait Locus Regulating Compensatory Renal Growth in the Rat.
Rat, compensatory renal growth, QTL, chromosome 4.
EB - Genetika a molekulární biologie
- 2000 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass
To dissect the major determinants of left ventricular mass (LVM), we combined expression quantitative trait locus and quantitative trait transcript analyses of the cardiac transcriptome in the rat. Using t...
EB - Genetika a molekulární biologie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Segment of rat chromosome 20 regulates diet-induced augmentations in adiposity, glucose intolerance, and blood pressure.
Analysis of SHR.BN congenic strain revealed a quantitative trait locus that is associated with obesity and hypertension. A possible candidate gene, tumor necrosis factor alpha, was analysed in detail....
EB - Genetika a molekulární biologie
- 2003 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension
To identify renally expressed genes that influence risk for hypertension, we integrated expression quantitative trait locus (QTL) analysis of the kidney with genome-wide correlation analysis of renal expression profiles and...
EB - Genetika a molekulární biologie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Pharmacogenetic Analysis of Captopril Effects on Blood Pressure: Possible Role of the Ednrb (Endothelin Receptor Type B) Candidate Gene
a significant quantitative trait locus (QTL) on chromosome 15 near Ednrb candidate gene be modulated by the variants at the Ednrb locus......
EB - Genetika a molekulární biologie
- 2014 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Soybean cadmium concentration: validation of a QTL affecting seed cadmium accumulation for improved food safety
Soybean can accumulate considerable amounts of cadmium depending on soil conditions. As low cadmium concentration of soybean is of great interest in soy food production, a major quantitative trait locus described earlier fo...
GD - Hnojení, závlahy, zpracování půdy
- 2015 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Flanking the major Plum pox virus resistance locus in apricot with co-dominant markers (SSRs) derived from candidate resistance genes
, the resistance is controlled by a major quantitative trait locus that explains up to 70 resistance locus into polymerase chain reaction markers (SSCP and SSR) and tested for their co-localisation with the major P...
GE - Šlechtění rostlin
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Plzf as a Candidate Gene Predisposing the Spontaneously Hypertensive Rat to Hypertension, Left Ventricular Hypertrophy, and Interstitial Fibrosis
BACKGROUND The spontaneously hypertensive rat (SHR) is the most widely used model of essential hypertension and is susceptible to left ventricular hypertrophy (LVH) and myocardial fibrosis. Recently, a quantitative trait locus
EB - Genetika a molekulární biologie
- 2014 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Rat model of familial combined hyperlipidemia as a result of comparative mapping
Total genome scan was carried out in 266 F2 hybrids of Lewis and Prague hypetriglyceridemic (HTG) rats which share some characteristics of human metabolic syndrome. Obtained data suggest a close relationship between dyslipidemia of HTG rats and human...
EB - Genetika a molekulární biologie
- 2004 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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