Filters
In vitro reactivation potency of acetylcholinesterase reactivators - K074 and K075 - to reactivate tabun-inhibited human brain cholinesterases
Reactivation activity of K074 and K075 in human brain in vitro...
FR - Farmakologie a lékárnická chemie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Structure-activity relationship of acetylcholinesterase reactivators
There is no single acetylcholinesterase reactivator for the treatment for the development of a universal so-called broad-spectrum reactivator. Unfortunately available oximes and their reactivation activity should be known t...
FP - Ostatní lékařské obory
- 2009 •
- C
Rok uplatnění
C - Kapitola v odborné knize
Evaluation of newly synthesized reactivators of the brain cholinesterase inhibited by sarin-nerve agent
In this work in vitro evaluation of the reactivation potency of the newly synthesized reactivators for acetylcholinesterase (AChE; EC 3.1.1.7) is described.Using this method, reactivation potency of twenty-one potential
FP - Ostatní lékařské obory
- 2005 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
In vitro reactivation potency of bispyridinium (E)-but-2-ene linked acetylcholinesterase reactivators against tabun-inhibited acetylcholinesterase
Six potential reactivators of acetylcholinesterase were prepared and evaluated for their reactivation potency...
FR - Farmakologie a lékárnická chemie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
In vitro screening of oxime reactivators on the model of paraoxon-inhibited acetylcholinesterase - SAR study
Screening of reactivation potency was performed with two concentrations of reactivator using rat brain homogenate as the source of AChE. Results were compared with established reactivators pralidoxime, methoxime, HI-6, trim...
FR - Farmakologie a lékárnická chemie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Synthesis of the novel AChE reactivators and their ability to reactivate in vitro chlorpyrifos-inhibited AChE
Synthesis of the novel AChE reactivators and their ability to reactivate in vitro chlorpyrifos-inhibited AChE.
FP - Ostatní lékařské obory
- 2005 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
In vitro reactivation of acetylcholinesterase using the oxime K027
-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium)propane dibromide] to reactivate the enzyme agent wereused as nerve agents. Its reactivation potency was compared to currently used acetylcholinesterase reactivators suc...
FP - Ostatní lékařské obory
- 2004 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Photometric microplate assay for estimation of paraoxon inhibited acetylcholinesterase reactivation efficacy
acetylcholinesterase (AChE). Three reactivators were used for reactivation purposes: obidoxime, pralidoxime, and HI-6. 3-D graphs (percent of reactivation vs. concentration of reactivator and vs. time of react...
FP - Ostatní lékařské obory
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Comparison of efficacy acetylcholiesterase reactivators inhibited by tabun
It was studied structure of acetylcholinesterase reactivators on efficacy of reactivation process. The best seems to be reactivators with two oxime groups in position 4 and involving three or four carbon spacer....
FP - Ostatní lékařské obory
- 2005 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study
We have tested three new promising bisquaternary AChE reactivators: K027, K033 and K048; reactivator K048 (reactivation 40%) surpassed all reactivators tested in this study......
CE - Biochemie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
- 1 - 10 out of 10 215