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Voltage and frequency dependent block of sodium current in cardiac cells: comparison of the effect of antiarrhythmic drugs
Voltage and frequency dependent block of sodium current in cardiac cells: comparison of the effect of antiarrhythmic drugs...
ED - Fyziologie
- 2002 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Determining limit currents in the electrodialysis of sodium chloride solutions
The lecture deals with determining limit currents in the electrodialysis of sodium chloride solutions. The aim of work was determined limit currents of sodium chloride solutin in laboratory, pilot and industrial el...
JP - Průmyslové procesy a zpracování
- 2013 •
- D
Rok uplatnění
D - Stať ve sborníku
Effect of block of fast sodium current and transient potassium current on configuratiom of action voltage in cardiac cells. (Computer modelling).
Quantitative models of use dependent block of fast sodium current (INa) and transient outward currentI (Ito) were integrated into total models of electrical activity of cardiac cells and the effect of drugs on action voltage were si...
BO - Biofyzika
- 2000 •
- D
Rok uplatnění
D - Stať ve sborníku
Citalopram effect on rapid sodium currents in tissue culture of hearth cells
Antidepressive, Citalopram, cardiotoxicity...
FL - Psychiatrie, sexuologie
- 2004 •
- C
Rok uplatnění
C - Kapitola v odborné knize
Effects of a persistent sodium current through mutated hNav1.5 sodium channels on intracellular ionic homeostasis in a ventricular cell model
In LQT3 patients, SCN5A mutations were found that lead to a small fraction of persistent hNav1.5 current. We explored the effects of such a change on the intracellular ionic homeostasis and arrhythmogenesis in a model of guinea-pig cardiac v...
ED - Fyziologie
- 2005 •
- D
Rok uplatnění
D - Stať ve sborníku
Voltage and frequency dependent block of sodium current in cardiac cells. Comparison of the effect of two antiarrhythmic drugs.
Ionic currents recorded in voltage clamp experiments on enzymatically isolated rat ventricular myocytes were analyzed with the aim to study the voltage and frequency dependence of sodium current block induced by two antiarr...
BO - Biofyzika
- 2002 •
- D
Rok uplatnění
D - Stať ve sborníku
Effect of antipsychotic drug perphenazine on fast sodium current and transient outward potassium current in rat ventricular myocytes
Perphenazine reversibly blocked fast sodium current INa (reducing its amplitude; IC50 = 1.24 microM) and transient outward potassium current Ito (accelerating its apparent inactivation with a slight decrease of its amplitud...
ED - Fyziologie
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Kinetics of propafenone-induced block of sodium current in rat ventricular myocytes
ED - Fyziologie
- 1997 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Perphenazine-induced block of sodium and transient outward potassium current: experimental and simulation study
The effect of a neuroleptic drug perphenazine on sodium current INa and transient outward potassium current Ito was studied in rat ventricular myocytes at room temperature. Perphenazine reversibly blocked INa (reducing its ...
BO - Biofyzika
- 2008 •
- D
Rok uplatnění
D - Stať ve sborníku
Perphenazine-Induced block of sodium and transient outward potassium current: experimental and simulation study
The effect of a neuroleptic drug perphenazine on sodium current INa and transient outward potassium current Ito was studied in rat ventricular myocytes at room temperature. Perphenazine reversibly blocked INa (reducing its ...
ED - Fyziologie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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