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Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells
autophagy. Pretreatment with a V-ATPase inhibitor bafilomycin, ellipticine induced resistance in these cells. The upregulation of a vacuolar (V)-ATPase with this finding, we found that levels of V
CE - Biochemie
- 2015 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Drug Sequestration in Lysosomes as One of the Mechanisms of Chemoresistance of Cancer Cells and the Possibilities of Its Inhibition
by the activity of the V-ATPase. This sequestration can be successfully inhibited by lysosomotropic agents and V-ATPase inhibitors in experimental conditions. Clinical trials tyrosine kinase inhibitor...
Oncology
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Drug Sequestration in Lysosomes as One of the Mechanisms of Chemoresistance of Cancer Cells and the Possibilities of Its Inhibition
by the activity of the V-ATPase. This sequestration can be successfully inhibited by lysosomotropic agents and V-ATPase inhibitors in experimental conditions. Clinical trials tyrosine kinase inhibitor...
Biochemistry and molecular biology
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomes
understood. Upon blocking endosomal acidification by the vacuolar ATPase (V-ATPase) inhibitors bafilomycin A1 (BafA1) or concanamycin A, we observed a significantly reduced apoptosis. Incells pretreated with these...
EB - Genetika a molekulární biologie
- 2013 •
- Jx •
- Link
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Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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Towards Novel PII-Type ATPase Inhibitors
Na+/K+-ATPase is an integral membrane protein that transports sodium and potassium ions against an electrochemical gradient. It belongs to the family of P-type ATPases that is structurally typified by the L-2-haloacid dehalogenase. ...
Nano-materials (production and properties)
- 2018 •
- C
Rok uplatnění
C - Kapitola v odborné knize
Activation of Porcine Oocytes Using Cyclopianonic Acid an Inhibitor of Calcium - Dependent ATPases
In vitro matured oocytes were activated using cyclopiazonic acid, an inhibitor of calcium dependent ATPases. The relase of intracellular calcium deposits was observed after CPA-treatment. Parthenogenetic development did not proceed ...
EI - Biotechnologie a bionika
- 2000 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Cyclopiazonic acid, an inhibitor of calcium-dependent ATPases, induCES exit from metaphase I arrest in growing pig oocytes.
Growing pig oocytes with partially meiotic competence were treated with cyclopiazonic acid, an inhibitor of calcium dependent ATPases. This treatment induced the progress of meiosis beyond the stage of metpahase I and enables the co...
ED - Fyziologie
- 2000 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Thapsigargin, a selective inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases, modulates nitric oxide production and cell death of primary rat hepatocytes in culture
cell death of cultured rat hepatocytes, effect of thapsigargin and nitric oxide...
FR - Farmakologie a lékárnická chemie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Diphyllin Shows a Broad-Spectrum Antiviral Activity against Multiple Medically Important Enveloped RNA and DNA Viruses
Diphyllin is a natural arylnaphtalide lignan extracted from tropical plants of particular importance in traditional Chinese medicine. This compound has been described as a potent inhibitor of vacuolar (H+)ATPases and hence of the en...
Microbiology
- 2022 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Inhibition of mitochondrial ATPase by dicarbopolyborate, a new enzyme inhibitor.
Annotation not available...
ED - Fyziologie
- 1994 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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