Impact of Vestibular Lesions on Allocentric Navigation and Interval Timing: The Role of Self-Initiated Motion in Spatial-Temporal Integration

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00454630" target="_blank" >RIV/67985823:_____/15:00454630 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1163/22134468-03002053" target="_blank" >http://dx.doi.org/10.1163/22134468-03002053</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1163/22134468-03002053" target="_blank" >10.1163/22134468-03002053</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of Vestibular Lesions on Allocentric Navigation and Interval Timing: The Role of Self-Initiated Motion in Spatial-Temporal Integration

Popis výsledku v původním jazyce

Bilateral intratympanic sodium arsenate injections (100 mg/ml in isotonic saline) in adult male Long Evans rats produced impairments in allocentric navigation using a 12-arm radial maze procedure as well as a motor test battery designed to evaluate vestibular function. In contrast, no impairments in the accuracy or precision of duration reproduction using 20-s and 80-s peak-interval procedures were observed when both target durations were associated with the same lever response, but distinguished by signal modality (e.g., light or sound). In contrast, an ordinal-reproduction procedure with 800, 3200, and 12,800 ms standards requiring the timing of self-initiated movements during the production phase revealed large impairments in the accuracy and precision of timing for vestibular lesioned rats. These impairments were greater on trials in which self-initiated body movements (e.g., holding down the response lever for a fixed duration) were required without the support of external stimuli

Název v anglickém jazyce

Impact of Vestibular Lesions on Allocentric Navigation and Interval Timing: The Role of Self-Initiated Motion in Spatial-Temporal Integration

Popis výsledku anglicky

Bilateral intratympanic sodium arsenate injections (100 mg/ml in isotonic saline) in adult male Long Evans rats produced impairments in allocentric navigation using a 12-arm radial maze procedure as well as a motor test battery designed to evaluate vestibular function. In contrast, no impairments in the accuracy or precision of duration reproduction using 20-s and 80-s peak-interval procedures were observed when both target durations were associated with the same lever response, but distinguished by signal modality (e.g., light or sound). In contrast, an ordinal-reproduction procedure with 800, 3200, and 12,800 ms standards requiring the timing of self-initiated movements during the production phase revealed large impairments in the accuracy and precision of timing for vestibular lesioned rats. These impairments were greater on trials in which self-initiated body movements (e.g., holding down the response lever for a fixed duration) were required without the support of external stimuli

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

<a href="/cs/project/LH14053" target="_blank" >LH14053: Čtvrtá dimenze v prostoru? Integrace časového a prostorového zpracování v mozku</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Timing & Time Perception

ISSN

2213-445X

e-ISSN

—

Svazek periodika

3

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

37

Strana od-do

269-305

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—