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Thermodynamic and kinetic investigations of metal complexes of polydentate ligands for biomedical, analytical and industrial applications

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    INTER-EXCELLENCE

  • Call for proposals

    SMSM2020LTC01

  • Main participants

    Univerzita Karlova / Přírodovědecká fakulta

  • Contest type

    VS - Public tender

  • Contract ID

    MSMT-21080/2020-21

Alternative language

  • Project name in Czech

    Thermodynamic and kinetic investigations of metal complexes of polydentate ligands for biomedical, analytical and industrial applications

  • Annotation in Czech

    In the Project, new experimental techniques for investigation of metal ion-ligand systems will be sought and tested. The metal considered metal ions are divalent (mainly Cu(II) and Pb(II)) and high-valent (Sc(III), Ga(III), lanthanide(III), Bi(III) and/or Zr(IV)) ones. These metal ions are those with radioisotopes of medicinal interest. The ligands to be studied are macrocyclic polydentate ligands and ligands of industrial interest as polyamino-polyphosphonates. For these systems, both thermodynamic and kinetic parameters are important and will be determined. The developed methods will be applied on systems with newly synthesized ligands to have data for a design of ligands with improved radiochemical properties. The ligands will be synthesized and evaluated to confirm the expectations based on the previous data.

Scientific branches

  • R&D category

    ZV - Basic research

  • OECD FORD - main branch

    10402 - Inorganic and nuclear chemistry

  • OECD FORD - secondary branch

    10406 - Analytical chemistry

  • OECD FORD - another secondary branch

  • CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    CA - Inorganic chemistry<br>CB - Analytical chemistry, separation<br>CH - Nuclear and quantum chemistry, photo chemistry

Solution timeline

  • Realization period - beginning

    Jun 1, 2020

  • Realization period - end

    Sep 30, 2023

  • Project status

    K - Ending multi-year project

  • Latest support payment

    Feb 25, 2022

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP23-MSM-LT-R

  • Data delivery date

    Sep 5, 2023

Finance

  • Total approved costs

    4,890 thou. CZK

  • Public financial support

    4,890 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK