Photoredox catalysis with redox inactive metal ions: A novel approach towards effective C–H functionalisations
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
SGA0202600001
Main participants
Vysoká škola chemicko-technologická v Praze / Fakulta chemické technologie
Contest type
VS - Public tender
Contract ID
26-22313S
Alternative language
Project name in Czech
Photoredox catalysis with redox inactive metal ions: A novel approach towards effective C–H functionalisations
Annotation in Czech
Replacement of iridium- and ruthenium-based catalysts with less expensive and more abundant alternatives represents a long-standing but still unresolved challenge in photoredox catalysis. An innovative solution could be the use of metal ions, such as Sc(III), Y(III), Zn(II) or Mg(II), which are considered redox- and photo-inactive species. Redox-inactive metal ions are presently used exclusively as Lewis acids and no one has yet considered using them as photoredox catalysts. Nevertheless, our preliminary experiments revealed a surprising photocatalytic activity of Sc(III) ions. Our project aim is to introduce redox-inactive metal ions as simple photoredox catalysts and use them to develop novel methodologies for oxidative functionalisation of various types of C–H bonds (benzylic, aromatic, and alpha-amino-sp3, as well as aliphatic), allowing C–O, C–S, C–N and C–C bond formation. The new photocatalytic systems will work under aerobic conditions with visible light and will be based on the oxophilicity of a redox-inactive metal ion and the metal ion-coupled electron transfer.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10401 - Organic chemistry
OECD FORD - secondary branch
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OECD FORD - another secondary branch
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CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
CC - Organic chemistry
Solution timeline
Realization period - beginning
Jan 1, 2026
Realization period - end
Dec 31, 2028
Project status
Z - Beginning multi-year project
Latest support payment
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Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP26-GA0-GA-R
Data delivery date
Apr 29, 2026
Finance
Total approved costs
7,604 thou. CZK
Public financial support
7,280 thou. CZK
Other public sources
270 thou. CZK
Non public and foreign sources
54 thou. CZK