Dynamic structure and function of the cell nucleus after irradiation
Project goals
changes of structure of chromatin caused by low doses of ionizating radiation, changes of nucleus topology of chromatine
Keywords
dynamic structurefunctioncell nucleusirradiationchromatinetopologyionizating radiation
Public support
Provider
Ministry of Education, Youth and Sports
Programme
Programme of regional and international cooperation in R&D (National programme of research)
Call for proposals
Regionální a mezinárodní spolupráce ve výzkumu 2 (SMSM2004001P2)
Main participants
—
Contest type
VS - Public tender
Contract ID
10 074/2005-32
Alternative language
Project name in Czech
Dynamická struktura a funkce buněčného jádra po ozáření
Annotation in Czech
změny struktury chromatinu vyvolané nízkými dávkami ionizujícího záření, zmeny jaderné topologie chromatinu
Scientific branches
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
DSBs induced by gama-radiation arise predominantly in sparse chromatin. DSB repair takes place in sites of their origin, where it is accompanied by chromatin decondensation manifested as DSB movement for short distance.
Solution timeline
Realization period - beginning
Jan 1, 2005
Realization period - end
Dec 31, 2007
Project status
U - Finished project
Latest support payment
Feb 26, 2007
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP08-MSM-1P-U/01:1
Data delivery date
Jun 26, 2008
Finance
Total approved costs
2,522 thou. CZK
Public financial support
1,043 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
1,479 thou. CZK
Basic information
Recognised costs
2 522 CZK thou.
Public support
1 043 CZK thou.
41%
Provider
Ministry of Education, Youth and Sports
CEP
BO - Biophysics
Solution period
01. 01. 2005 - 31. 12. 2007