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7E08027

Large scale interactions in brain networks and their breakdown in brain diseases

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

  • Call for proposals

    FP7-HEALTH-2007-A

  • Main participants

  • Contest type

    RP - Co-financing of EC programme

  • Contract ID

    3094/2010-32

Alternative language

  • Project name in Czech

    Large scale interactions in brain networks and their breakdown in brain diseases

  • Annotation in Czech

    The long-term goal of this project is to understand how neuronal assemblies exchange information (functional or neuronal communication), and how variability in neuronal communication explains variability in behavioural performance, both in the intact andinjured brain. Communication involves temporal interactions between neuronal assemblies either locally within an area or large-scale between areas. We concentrate on large-scale interaction that occur at two different temporal scales: 'slow' (<0.1 Hz) fluctuations of the blood oxygen level dependent (BOLD) signal easily measured with functional magnetic resonance imaging (fMRI), and 'fast' (1-150 Hz) neuronal oscillations measured at high (multi-unit activity (MUA), local field potential (LFP)) or low(electroencephalography, EEG; magnetoencephalography, MEG) spatial resolution. We wish to demonstrate that these two phenomena are mechanistically linked and are behaviorally significant. A potentially important clinical application is the

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    FH - Neurology, neuro-surgery, nuero-sciences

  • CEP - secondary branch

    IN - Informatics

  • CEP - another secondary branch

    BB - Applied statistics, operational research

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10103 - Statistics and probability<br>10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)<br>30103 - Neurosciences (including psychophysiology)<br>30210 - Clinical neurology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.

Solution timeline

  • Realization period - beginning

    Mar 1, 2008

  • Realization period - end

    Feb 28, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Mar 7, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MSM-7E-U/01:1

  • Data delivery date

    Jul 12, 2012

Finance

  • Total approved costs

    2,237 thou. CZK

  • Public financial support

    2,237 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK