Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization.
Public support
Provider
Ministry of Education, Youth and Sports
Programme
—
Call for proposals
FP7-Health-2009-two-stage
Main participants
—
Contest type
RP - Co-financing of EC programme
Contract ID
3096/2010-32
Alternative language
Project name in Czech
Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization.
Annotation in Czech
Stem cells offer a promising avenue to therapy for a wide range of complaints. However, for this potential to be realized, a consistent and plentiful supply of well-characterised stem cells is essential. There has been relatively little progress in the development of new culture technologies for the large-scale manufacture of mesenchymal stem cells (MSCs). There are no standards for characterisation, isolation or identification of MSCs from any tissue, nor are there standard protocols for differentiation of MSCs to various lineages. Additionally, surface markers used for MSC characterization lack specificity and cryopreservation protocols are not standardized. PurStem will: - Identify the MSC ?receptome? and, - Use this repertoire of growth factor receptors to, - Develop novel serum-free media for MSC production.
Scientific branches
R&D category
AP - Applied research
CEP classification - main branch
EA - Morphology and cytology
CEP - secondary branch
EC - Immunology
CEP - another secondary branch
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OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10601 - Cell biology<br>10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology<br>30102 - Immunology
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.
Solution timeline
Realization period - beginning
Nov 1, 2009
Realization period - end
Oct 31, 2011
Project status
U - Finished project
Latest support payment
Mar 10, 2011
Data delivery to CEP
Confidentiality
C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.
Data delivery code
CEP12-MSM-7E-U/01:1
Data delivery date
Jul 12, 2012
Finance
Total approved costs
2,659 thou. CZK
Public financial support
2,659 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK