European large-scale functional genomics in the rat for translational research
Public support
Provider
Ministry of Education, Youth and Sports
Programme
—
Call for proposals
FP7-HEALTH-2010-two-stage
Main participants
—
Contest type
RP - Co-financing of EC programme
Contract ID
MSMT-1838/2013-310
Alternative language
Project name in Czech
European large-scale functional genomics in the rat for translational research
Annotation in Czech
Genetic studies in model organisms and humans, including human genome-wide association studies, have pinpointed genomic regions that contribute susceptibility to common disease. However, to date, these data have provided limited insights into the genes,molecular pathways and mechanisms underlying disease pathophysiology. The EU FP6 Euratools consortium has been a remarkable success that established significant research collaborations, expertise and infrastructure in the EU, making a major contributionto the rat focus issue of Nature Genetics (Volume 40, May 2008), which featured six papers from the consortium. These successes underpin the current project in which we will use state-of-the-art and emerging large-scale technologies and advanced computation in an expanded multi-disciplinary approach to identify gene networks and genomic mechanisms underlying common diseases. We will use the rat as a model system to identify the major functional pathways underlying human inflammatory, cardiovasc
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
ED - Physiology
CEP - another secondary branch
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30105 - Physiology (including cytology)<br>30202 - Endocrinology and metabolism (including diabetes, hormones)
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.
Solution timeline
Realization period - beginning
Apr 1, 2010
Realization period - end
Oct 31, 2014
Project status
U - Finished project
Latest support payment
Mar 12, 2014
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP15-MSM-7E-U/01:1
Data delivery date
Jul 2, 2015
Finance
Total approved costs
2,707 thou. CZK
Public financial support
2,707 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK