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7E11070

Systems biology of Mycobacterium tuberculosis

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

  • Call for proposals

    FP7-Health-2009-two-stage

  • Main participants

  • Contest type

    RP - Co-financing of EC programme

  • Contract ID

    MSMT-1839/2013-310

Alternative language

  • Project name in Czech

    Systems biology of Mycobacterium tuberculosis

  • Annotation in Czech

    The goal of the SysteMTb project is to establish a Systems Biology framework to understand key features of Mtb and its interactions with the host which in turn will provide new insights and a solid (model based) knowledge for the development of novel strategies to combat tuberculosis. The consorcium plan to generate and integrate quantitative data sets of Mtb: transcriptomics, proteomics, metabolomics, structural genomics, lipidomics, glycomics under different environmental perturbations both in the isolated bacterium, as well as in the bacterium encountering the macrophages. Protein function and structure will be also investigated. Modelling will provide a modelling scaffold to study Mtb internal wiring and dynamic interplay within a host environment.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EE - Microbiology, virology

  • CEP - secondary branch

    CE - Biochemistry

  • CEP - another secondary branch

    EC - Immunology

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10606 - Microbiology<br>10607 - Virology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30102 - Immunology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.

Solution timeline

  • Realization period - beginning

    Jan 1, 2011

  • Realization period - end

    Sep 30, 2014

  • Project status

    U - Finished project

  • Latest support payment

    Mar 20, 2014

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP15-MSM-7E-U/01:1

  • Data delivery date

    Jul 2, 2015

Finance

  • Total approved costs

    3,498 thou. CZK

  • Public financial support

    3,498 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK