Czech node of INFRAFRONTIER - The European infrastructure for phenotyping and archiving of model mammalian genomes
Project goals
The project supports the establishment of the Czech Centre of Phenogenomics (CCP) and prepares its full integration into the international consortium Infrafrontier. Infrafrontier deals with systematic, standardized, functional annotation of genes using animal models and the main goal of the Czech partner is to establish own program of ?functional genomics? including infrastructure for generation of genetically modified mouse models, their cryo-archiving, and their distribution to the users and researches. This project establishes functional analysis of the role of individual genes in cooperation with international and Czech partners. CCP creates great opportunities for individual specialized research groups as it provides functional description of genefunction in many individual organs and all main physiological systems. Thus, the individual specialized research groups can effectively characterize molecular mechanisms that provide fundament to reveal specific phenotypes. Program and preparation period for integration of CCP into the international consortium cover two main fields: archiving and distribution of mouse models/mutants (Archivefrontier/EMMA, European mouse mutant archive) and phenotyping (Phenomefrontier, i.e. functional characterizationof genes)
Keywords
genemutationphenotypisationcryopreservationmouse modelsarchiving and distribution of mouse models
Public support
Provider
Ministry of Education, Youth and Sports
Programme
—
Call for proposals
FP7-INFRASTRUCTURES-2007-2
Main participants
—
Contest type
RP - Co-financing of EC programme
Contract ID
34668/2012-32
Alternative language
Project name in Czech
České centrum INFRAFRONTIER - The European infrastructure for phenotyping and archiving of model mammalian genomes
Annotation in Czech
Projekt přispívá k etablování Českého Centra Fenogenomiky (CCP, Czech Centre for Phenogenomics) a připravuje ho k napojení na mezinárodní konsorcium Infrafrontier. Infrafrontier se zabývá systematickou standardizovanou funkční anotací genů pomocí zvířecích modelů a hlavním cílem českého partnera je etablování programu funkční genomiky, tvorby geneticky změněných myších modelů a jejich kryoarchivování a distribuce uživatelům. Tento projekt připravuje funkční analýzu role jednotlivých genů v kooperaci s mezinárodními a českými partnery. Při popisu fenotypů mutantních modelů v jednotlivých orgánech či fyziologých celcích vytváří CCP velký potenciál pro jednotlivé specializované vědecké skupiny, které pak mohou efektivně charakterizovat molekulární mechanismy funkc genů, jež se odráží ve specifickém fenotypu. Program i příprava zapojení jsou funkčně rozděleny do dvou oblastí: archivace a distribuce myších modelů/mutantů (Archivefrontier/EMMA, European mouse mutant archive) a fenotypizace (Phenomefrontier,t.j. funkční charakterizace genu).
Scientific branches
R&D category
IF - RDI infrastructure
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
ED - Physiology
CEP - another secondary branch
FB - Endocrinology, diabetology, metabolism, nutrition
10603 - Genetics and heredity (medical genetics to be 3)
10604 - Reproductive biology (medical aspects to be 3)
10605 - Developmental biology
10608 - Biochemistry and molecular biology
10609 - Biochemical research methods
30101 - Human genetics
30105 - Physiology (including cytology)
30202 - Endocrinology and metabolism (including diabetes, hormones)
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.
Solution timeline
Realization period - beginning
Jan 1, 2012
Realization period - end
Dec 31, 2012
Project status
U - Finished project
Latest support payment
Nov 29, 2012
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP13-MSM-7E-U/01:1
Data delivery date
Jun 28, 2013
Finance
Total approved costs
295 thou. CZK
Public financial support
295 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK
Recognised costs
295 CZK thou.
Public support
295 CZK thou.
0%
Provider
Ministry of Education, Youth and Sports
CEP
EB - Genetics and molecular biology
Solution period
01. 01. 2012 - 31. 12. 2012