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7E13008

Next Generation Sequencing Platform for Targeted Personalized Therapy of Leukemia

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

  • Call for proposals

    FP7-HEALTH-2012-INNOVATION-1

  • Main participants

    Masarykova univerzita / Středoevropský technologický institut

  • Contest type

    RP - Co-financing of EC programme

  • Contract ID

    MSMT-42111/2013

Alternative language

  • Project name in Czech

    Next Generation Sequencing Platform for Targeted Personalized Therapy of Leukemia

  • Annotation in Czech

    This project aims at developing a European Hematological/HTS platform of scientists for improving outcomes for therapeutic interventions on acute and chronic leukemias and at develop strategies to personalize treatments and tailor therapies to differentstratified groups of leukemia patients, with the goal of optimizing their efficacy and safety through a deeper and deeper understanding of the influence of genetic/genomic alterations on leukemias pathogenesis and treatment response (i.e. ?personalized therapy?). Moreover, the final aim will be the identification of novel prognostic biomarkers for acute and chronic leukemias, as well as of molecular biomarkers and/or genomic profiles for the assessment of minimal residual disease. The originality of this project is to perform systematic deep genomic/transcriptomic studies on well-clinically-characterized leukemia patients, by exploiting HTS technologies able to quickly produce data with a good cost-effectiveness and an unprecedented resolution.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    FD - Oncology and haematology

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30204 - Oncology<br>30205 - Hematology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.

Solution timeline

  • Realization period - beginning

    Jan 1, 2013

  • Realization period - end

    Oct 31, 2015

  • Project status

    U - Finished project

  • Latest support payment

    Mar 20, 2014

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP16-MSM-7E-U/01:1

  • Data delivery date

    Oct 6, 2017

Finance

  • Total approved costs

    3,114 thou. CZK

  • Public financial support

    3,114 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK