Improving Diagnoses of Mental Retardation in Children in Eastern Europe and Central Asia through Genetic Characterisation and Bioinformatics/Statistics

Provider

Ministry of Education, Youth and Sports

Programme

—

Call for proposals

FP7-Health-2009-two-stage

Main participants

—

Contest type

RP - Co-financing of EC programme

Contract ID

1086/2011-321

Project name in Czech

Improving Diagnoses of Mental Retardation in Children in Eastern Europe and Central Asia through Genetic Characterisation and Bioinformatics/Statistics

Annotation in Czech

Mental retardation (MR) is a highly heterogeneous disorder and is of genetic origin in about 50% of the cases. Despite recent progress in research the causes and the pathophysiology of MR remains obscure. It is essential to investigate this in order to develop future diagnostic and therapeutic strategies. The overall goal of this proposal is to establish an interdisciplinary Eastern Europe and Central Asia (EECA) consortium of experts with a joint programme of activities to generate knowledge about MR and the structure and dynamics of the brain as such. This project will be the first to study in depth the prevalence and incidence of MR in EECA. The objectives of the CHERISH project are to: - develop a standardized approach for MR diagnosis through clinical workshops and courses; - create a large data-base of patients with clinically well defined MR, both syndromic and non-syndromic; - identify cryptic genomic rearrangements through molecular cytogenetic analysis; - sequence MR genes and analyse the m

R&D category

ZV - Basic research

CEP classification - main branch

EB - Genetics and molecular biology

CEP - secondary branch

FP - Other medical fields

CEP - another secondary branch

FG - Paediatrics

OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30106 - Anatomy and morphology (plant science to be 1.6)<br>30107 - Medicinal chemistry<br>30108 - Toxicology<br>30109 - Pathology<br>30209 - Paediatrics<br>30221 - Critical care medicine and Emergency medicine<br>30223 - Anaesthesiology<br>30224 - Radiology, nuclear medicine and medical imaging<br>30225 - Allergy<br>30226 - Rheumatology<br>30227 - Geriatrics and gerontology<br>30229 - Integrative and complementary medicine (alternative practice systems)<br>30230 - Other clinical medicine subjects<br>30307 - Nursing<br>30308 - Nutrition, Dietetics<br>30309 - Tropical medicine<br>30310 - Parasitology<br>30311 - Medical ethics<br>30312 - Substance abuse<br>30501 - Forensic science<br>30502 - Other medical science

Provider evaluation

U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

Project results evaluation

Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.

Realization period - beginning

Feb 1, 2009

Realization period - end

Jan 31, 2012

Project status

U - Finished project

Latest support payment

Mar 10, 2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data delivery code

CEP13-MSM-7E-U/01:1

Data delivery date

Jun 28, 2013

Total approved costs

1,435 thou. CZK

Public financial support

1,435 thou. CZK

Other public sources

0 thou. CZK

Non public and foreign sources

0 thou. CZK