Infections in the pathogenesis of type 1 diabetes: The MIDIA study
Project goals
Type 1 diabetes is caused by organ specific autoimmunity resulting from gene-environmental interactions. The main goal of the pediatric diabetes research, including our project, is to improve the quality of life of children with diabetes or their families; in our case this applies to children at prospective risk of type 1 diabetes. Non-genetic factors have so far been difficult to demonstrate. Certain infections or getting too few infections in early childhood are among the strongest candidate factors.The overall objective of this project is to assess the role of infections in development of type 1 diabetes. The MIDIA (the Norwegian acronyme for environmental triggers of type 1 diabetes) identifies at birth the babies with the higest genetic risk fortype 1 diabetes, and follows them regularly with stool samples, blood samples and questionnaires. This is done to assess candidate environmental exposures potentially triggering processes leading to type 1 diabetes. The environmental infectious ex
Keywords
type 1 diabetesinfectionmolecular epidemiologyparechovirusenterovirusautoimmunity
Public support
Provider
Ministry of Education, Youth and Sports
Programme
EEA/Norwegian Financial Mechanism
Call for proposals
—
Main participants
—
Contest type
RP - Co-financing of EC programme
Contract ID
4 726/2009-32
Alternative language
Project name in Czech
Infections in the pathogenesis of type 1 diabetes: The MIDIA study
Annotation in Czech
Type 1 diabetes is caused by organ specific autoimmunity resulting from gene-environmental interactions. The main goal of the pediatric diabetes research, including our project, is to improve the quality of life of children with diabetes or their families; in our case this applies to children at prospective risk of type 1 diabetes. Non-genetic factors have so far been difficult to demonstrate. Certain infections or getting too few infections in early childhood are among the strongest candidate factors.The overall objective of this project is to assess the role of infections in development of type 1 diabetes. The MIDIA (the Norwegian acronyme for environmental triggers of type 1 diabetes) identifies at birth the babies with the higest genetic risk fortype 1 diabetes, and follows them regularly with stool samples, blood samples and questionnaires. This is done to assess candidate environmental exposures potentially triggering processes leading to type 1 diabetes. The environmental infectious ex
Scientific branches
R&D category
AP - Applied research
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
FB - Endocrinology, diabetology, metabolism, nutrition
CEP - another secondary branch
EE - Microbiology, virology
10603 - Genetics and heredity (medical genetics to be 3)
10604 - Reproductive biology (medical aspects to be 3)
10605 - Developmental biology
10606 - Microbiology
10607 - Virology
10608 - Biochemistry and molecular biology
10609 - Biochemical research methods
30101 - Human genetics
30202 - Endocrinology and metabolism (including diabetes, hormones)
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.
Solution timeline
Realization period - beginning
Jan 1, 2009
Realization period - end
Dec 31, 2009
Project status
U - Finished project
Latest support payment
May 19, 2009
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP10-MSM-7F-U/01:1
Data delivery date
Jun 30, 2010
Finance
Total approved costs
253 thou. CZK
Public financial support
253 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK
Basic information
Recognised costs
253 CZK thou.
Public support
253 CZK thou.
100%
Provider
Ministry of Education, Youth and Sports
CEP
EB - Genetics and molecular biology
Solution period
01. 01. 2009 - 31. 12. 2009