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7F09015

Infections in the pathogenesis of type 1 diabetes: The MIDIA study

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    EEA/Norwegian Financial Mechanism

  • Call for proposals

  • Main participants

  • Contest type

    RP - Co-financing of EC programme

  • Contract ID

    4 726/2009-32

Alternative language

  • Project name in Czech

    Infections in the pathogenesis of type 1 diabetes: The MIDIA study

  • Annotation in Czech

    Type 1 diabetes is caused by organ specific autoimmunity resulting from gene-environmental interactions. The main goal of the pediatric diabetes research, including our project, is to improve the quality of life of children with diabetes or their families; in our case this applies to children at prospective risk of type 1 diabetes. Non-genetic factors have so far been difficult to demonstrate. Certain infections or getting too few infections in early childhood are among the strongest candidate factors.The overall objective of this project is to assess the role of infections in development of type 1 diabetes. The MIDIA (the Norwegian acronyme for environmental triggers of type 1 diabetes) identifies at birth the babies with the higest genetic risk fortype 1 diabetes, and follows them regularly with stool samples, blood samples and questionnaires. This is done to assess candidate environmental exposures potentially triggering processes leading to type 1 diabetes. The environmental infectious ex

Scientific branches

  • R&D category

    AP - Applied research

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    FB - Endocrinology, diabetology, metabolism, nutrition

  • CEP - another secondary branch

    EE - Microbiology, virology

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10606 - Microbiology<br>10607 - Virology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30202 - Endocrinology and metabolism (including diabetes, hormones)

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.

Solution timeline

  • Realization period - beginning

    Jan 1, 2009

  • Realization period - end

    Dec 31, 2009

  • Project status

    U - Finished project

  • Latest support payment

    May 19, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP10-MSM-7F-U/01:1

  • Data delivery date

    Jun 30, 2010

Finance

  • Total approved costs

    253 thou. CZK

  • Public financial support

    253 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK