Analysis of Czech Genomes for Theranostics
Public support
Provider
Ministry of Education, Youth and Sports
Programme
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Call for proposals
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Main participants
Masarykova univerzita / Středoevropský technologický institut
Contest type
OP - EU Operational Programme
Contract ID
16_026/0008448-01
Alternative language
Project name in Czech
Analýza českých genomů pro teranostiku
Annotation in Czech
Cílem projektu je vytvoření národní referenční databáze - nástroje, který bude napovat genetickou variabilitu české populace. Na vzorku 1000 zdravých obyvatel bude provedeno celogenomové sekvenování a nasledně analýza získaných dat. Identifikované varianty budou spolu s jejich frekvencí v populaci vloženy do databáze. Tato data jsou nezbytná pro správnou interpretaci diagnostickách genetickách testů.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10603 - Genetics and heredity (medical genetics to be 3)
OECD FORD - secondary branch
30101 - Human genetics
OECD FORD - another secondary branch
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CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
EB - Genetics and molecular biology
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
There was developed a strategy for cooperation between organisations in the field of R&D. There was set up Intersectoral cooperation and rules for employees in cooperation with research organisations. Good laboratory practice guidelines were developed for the collection and management of clinical samples, the evaluation and interpretation of data for use in the clinical setting, a code of ethics for the management of sample identification and guidelines on ethical issues related to the genome. Project research has mainly involved the preparation of libraries for whole-genome sequencing, in-depth analysis of structural variants in whole-genome sequences, and digitization of data and metadata from collected samples. Collaboration in partnership among research organisations and the application sphere enables better transfer of knowledge and experience of the project, increases the standard of genomic methods and facilitates their dissemination in clinical practice.
Solution timeline
Realization period - beginning
Jan 1, 2019
Realization period - end
Jun 30, 2023
Project status
U - Finished project
Latest support payment
Sep 6, 2020
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP24-MSM-EF-U
Data delivery date
Jul 1, 2024
Finance
Total approved costs
73,378 thou. CZK
Public financial support
73,378 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK