Bridging the gap between system biology and machine learning
Project goals
The present rapid advent of bioinformatics has been producing enormous volumes of system biology knowledge bases which, if combined with empirical high-throughput data, may unveil novel biologically significant hypotheses. The sheer volume of the now existing knowledge bases prohibits any human researcher from taking them fully into account when forming a hypothesis. Algorithmic knowledge discovery enabled by machine learning systems seem to be a perfect candidate to take up this challenge, but currently these systems are not able to process the kinds of knowledge forms developed by bioinformaticians. In this project we propose to bridge this urgent gap by developing algorithms able to discover knowledge patterns from process networks, such as metabolic, gene-regulatory or cell signaling pathways, which represent the prevailing and most actionable knowledge form of current bioinformatics bases.
Keywords
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
Standardní projekty 12 (SGA02009GA-ST)
Main participants
—
Contest type
VS - Public tender
Contract ID
201/09/1665
Alternative language
Project name in Czech
Překonání propasti mezi systémovou biologií a strojovým učením
Annotation in Czech
Překonat propast mezi systémovou biologií a strojovým učením vytvořením algoritmů schopných těžit znalosti z procesních sítí, jako jsou metabolické, genově-regulační či buněčně-signální dráhy, které představují převažující a nejoperativnější formu znalostí v současných bioinformatických databázích.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
JC - Computer hardware and software
CEP - secondary branch
JD - Use of computers, robotics and its application
CEP - another secondary branch
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20204 - Robotics and automatic control
20205 - Automation and control systems
20206 - Computer hardware and architecture
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
The project gone according to plan both in terms of expertise and in terms of disbursement of funds.
Solution timeline
Realization period - beginning
Jan 1, 2009
Realization period - end
Dec 31, 2011
Project status
U - Finished project
Latest support payment
Apr 16, 2011
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP12-GA0-GA-U/02:2
Data delivery date
May 2, 2016
Finance
Total approved costs
1,983 thou. CZK
Public financial support
1,983 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK
Basic information
Recognised costs
1 983 CZK thou.
Public support
1 983 CZK thou.
100%
Provider
Czech Science Foundation
CEP
JC - Computer hardware and software
Solution period
01. 01. 2009 - 31. 12. 2011