Continuous unit operations for enantiomer separation using layers with ionic selectors
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
SGA0202600001
Main participants
Vysoká škola chemicko-technologická v Praze / Fakulta chemicko-inženýrská
Contest type
VS - Public tender
Contract ID
26-21718S
Alternative language
Project name in Czech
Continuous unit operations for enantiomer separation using layers with ionic selectors
Annotation in Czech
The project tackles the challenges of continuous separation of enantiomers by investigating the underlying transport and chiral recognition mechanisms, with the aim of proposing viable methods for the production of pharmaceutically important drugs, such as dexketoprofen, levothyroxine, or levofloxacin. Focusing on working mechanisms of enantioseparation, we will transform the features of facilitated and retarded transport into membranes possessing chiral selectivity. We will synthesize ionic conductive polymers and porous particles with ionic chiral centers based on chiral quinine selectors. These will work as chiral ion exchangers, which are especially suitable for the separation of ionic enantiomers. We will combine functional materials with microfluidic technologies to design several unit operations for electric field-enhanced enantioseparations. Our strategy covers the entire research line, from the preparation of chiral selectors and the functional design of new membranes to the testing of continuously operating membrane modules.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
20402 - Chemical process engineering
OECD FORD - secondary branch
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OECD FORD - another secondary branch
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CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
CI - Industrial chemistry and chemical engineering
Solution timeline
Realization period - beginning
Jan 1, 2026
Realization period - end
Dec 31, 2028
Project status
Z - Beginning multi-year project
Latest support payment
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Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP26-GA0-GA-R
Data delivery date
May 6, 2026
Finance
Total approved costs
12,972 thou. CZK
Public financial support
12,396 thou. CZK
Other public sources
480 thou. CZK
Non public and foreign sources
96 thou. CZK