Molecular basis of osmotolerant yeast Z. rouxii, Z. bailii and D. hansenii specific properties and their biotechnological applications
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
Standardní projekty 13 (SGA02010GA-ST)
Main participants
—
Contest type
VS - Public tender
Contract ID
P503-10-0307
Alternative language
Project name in Czech
Molekulární podstata specifických vlastností osmotolerantních kvasinek Z. rouxii, Z. bailii a D. hansenii a jejich biotechnologické aplikace
Annotation in Czech
Cílem projektu je charakterizovat specifické rysy nekonvenčních osmotolerantních kvasinek Debaryomyces hansenii, Zygosaccharomyces rouxii a Zygosaccharomyces bailii na molekulární úrovni a přispět tak ke zlepšení vlastností průmyslových kmenů Saccharomyces cerevisiae. Projekt se skládá ze tří částí: (1) izolace dosud neznámých genů důležitých pro transport fruktosy, glycerolu a kationů alkalických kovů a charakterizace jejich produktů, (2) vytvoření nových nástrojů genového inženýrství pro Z. bailii a D. hansenii, a 3) konstrukce a fenotypová charakterizace nových kmenů S. cerevisiae se zlepšenými růstovými/tolerančními vlastnostmi pomocí heterologní exprese genů izolovaných z nekonvenčních druhů kvasinek.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EI - Biotechnology and bionics
CEP - secondary branch
EB - Genetics and molecular biology
CEP - another secondary branch
EE - Microbiology, virology
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10606 - Microbiology<br>10607 - Virology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30101 - Human genetics<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
The project brought original information about the fructose, glycerol and potassium transporters in osmotolerant yeast species, and their possible use in biotechnology. The results were largely published or submitted for publication in impacted journals.No problems were found either in maintaining the grant rules or using the financial means.
Solution timeline
Realization period - beginning
Jan 1, 2010
Realization period - end
Dec 31, 2014
Project status
U - Finished project
Latest support payment
Mar 19, 2014
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP15-GA0-GA-U/01:1
Data delivery date
May 22, 2015
Finance
Total approved costs
5,551 thou. CZK
Public financial support
5,351 thou. CZK
Other public sources
200 thou. CZK
Non public and foreign sources
0 thou. CZK