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Characterisation of proteins comprising newly described translationally inactive ribonucleoprotein EPP particles during tobacco pollen development and maturatio

Project goals

A tobacco pollen tube wall glycoprotein, p69 is encoded by the pollen-specific gene ntp303 that is transcribed during pollen development and pollen tube growth, but it is abundantly translated only after pollen germination. ntp303/p69 represents the onlyknown example of a highly abundant pollen-specific mRNA, which is stored in mature pollen in a translationally-silent form. A significant part of ntp303 mRNA is stored in the form of newly identified translationally inactive ribonucleoprotein EPP particles that have been described based on their sedimentation characteristics and the protein composition of EPP-enriched cytoplasmic fraction. The abundant representation of stored ntp303 mRNA in the population of EPP particles clearly shows the existence ofan alternative cytoplasmic mRNA storage compartment in male gametophyte. The key objective of the proposed project is the precise biochemical characterisation of EPP particles and, moreover, the identification of proteins bound to ntp303 mRN

Keywords

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Post-graduate (doctorate) grants

  • Call for proposals

    Postdoktorandské granty 2 (SGA02002GA-PD)

  • Main participants

    Ústav experimentální botaniky AV ČR, v. v. i.

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Charakterizace bˇlkovin tvoýˇcˇch novŘ popsan? translaźnŘ neaktivnˇ ribonukleoproteinov? EPP ź stice bŘhem věvoje a zr nˇ pylu tab ku

  • Annotation in Czech

    StŘnově glykoprotein p69 izolovaně z˙pylověch l źek tab ku (Nicotiana tabacum) je k˘dovaně pylovŘ specifickěm genem ntp303, kterě je transkribovaně bŘhem věvoje pylu i r?stu pylov? l źky, ale k˙jeho§ masivnˇ translaci doch zˇ a§ po vyklˇźenˇ pylov?ho zrna. Syst?m ntp303/p69 tak pýedstavuje jedině zn mě pýˇklad vysoce abundantnˇ pylovŘ specifick? mRNA skladovan? v˙netranslatovateln? podobŘ. Velk  ź st ntp303 mRNA je skladov na ve formŘ novŘ popsaněch translaźnŘ neaktivnˇch ribonukleoproteinověch EPP ź stic, kter? byly zatˇm pops ny na z kladŘ sedimentaźnˇch charakteristik a bˇlkovinn?ho slo§enˇ EPP ź sticemi obohacen? cytoplasmatick? frakce. Abundantnˇ zastoupenˇ skladovan? ntp303 mRNA v populaci EPP ź stic ukazuje na existenci alternativnˇho cytoplasmatick?ho kompartmentu pro ukl d nˇ z sobnˇ mRNA v samźˇm gametofytu. Podstatou navrhovan?ho projektu je podrobn  biochemick  charakterisace EPP ź stic a d le identifikace bˇlkovin v §ˇcˇch se k˙ntp303 mRNA a podˇlejˇcˇch se na negativnˇ regulaci

Scientific branches

  • R&D category

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    ED - Physiology

  • CEP - another secondary branch

  • 10603 - Genetics and heredity (medical genetics to be 3)
    10604 - Reproductive biology (medical aspects to be 3)
    10605 - Developmental biology
    10608 - Biochemistry and molecular biology
    10609 - Biochemical research methods
    30101 - Human genetics
    30105 - Physiology (including cytology)

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Vzhledem k tomu, §e ýeçitel projekt pýedźasnŘ ukonźil po sedmi mŘsˇcˇch ýeçenˇ z d?vodu odchodu na zahraniźnˇ st §, nenˇ t?mŘý co hodnotit. Zˇskan? dˇlźˇ věsledky tak, jak je ýeçitel popisuje ve zpr vŘ a kter? prezentoval na jedn? dom cˇ konferenci, jsou

Solution timeline

  • Realization period - beginning

    Jan 1, 2001

  • Realization period - end

    Jan 1, 2004

  • Project status

    S - Stopped (prematurely terminated) multi-year project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP/2003/GA0/GA03GP/U/N/7:4

  • Data delivery date

    Jun 15, 2009

Finance

  • Total approved costs

    459 thou. CZK

  • Public financial support

    313 thou. CZK

  • Other public sources

    168 thou. CZK

  • Non public and foreign sources

    0 thou. CZK