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Revealing the pathohysiological function of serine protease kallikrein 14 in vivo using mouse models

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Post-graduate (doctorate) grants

  • Call for proposals

    Postdoktorandské granty 9 (SGA02009GA1PD)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    301/09/P662

Alternative language

  • Project name in Czech

    Objasnění patofyziologické funkce serinové proteázy kallikrein 14 in vivo s využitím myšších modelů

  • Annotation in Czech

    Charakterizovat funkci serinové proteázy kallikrein 14 (Klk14) in vivo pomocí dvou kondicionálních myších modelů. Studium deficientní myši (knockout) povede k objasnění fyziologické role Klk14. Vytvoření transgenní myši exprimující Klk14 v epidermis povede k posaní její úlohy v kutanní patologii.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    CE - Biochemistry

  • CEP - another secondary branch

    FO - Dermatology and venereology

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30216 - Dermatology and venereal diseases

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The project was excellent, both in terms of expertise and in terms of disbursement of funds.

Solution timeline

  • Realization period - beginning

    Jan 1, 2009

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Apr 16, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-GA0-GP-U/03:3

  • Data delivery date

    May 2, 2016

Finance

  • Total approved costs

    2,589 thou. CZK

  • Public financial support

    2,589 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK