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IZ3985

Phototoxic effects of xenobiotics - an in vitro test system

Project goals

The aim of the Project is to develop an alternative in vitro method for xenobiotics phototoxicity assessment to avoid testing on animals, using stabilized cell line tissue culture and detection of effect at cellular and subcellular level by fluorimetry.

Keywords

Public support

  • Provider

    Ministry of Health

  • Programme

  • Call for proposals

  • Main participants

    Státní zdravotní ústav

  • Contest type

  • Contract ID

Alternative language

  • Project name in Czech

    Fototoxické účinky xenobiotik - testovací systém in vitro

  • Annotation in Czech

    Vytvo°enÝ alternativnÝ metody in vitro pro testovßnÝ fototoxicity xenobiotik, , kterß omezÝ testovßnÝ na zvݰatech. Vyu×ije tk߲ovou kulturu stabilizovanřch liniÝ bunýk a detekci ˙Ŕinku na celulßrnÝ a subcelulßrnÝ ˙rovni fluorimetricky.

Scientific branches

  • R&D category

  • CEP classification - main branch

    FM - Hygiene

  • CEP - secondary branch

  • CEP - another secondary branch

  • 30304 - Public and environmental health

Solution timeline

  • Realization period - beginning

    Jan 1, 1997

  • Realization period - end

    Jan 1, 1999

  • Project status

    K - Ending multi-year project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP/1999/MZ0/MZ09IZ/V/2:2

  • Data delivery date

Finance

  • Total approved costs

    2,157 thou. CZK

  • Public financial support

    1,473 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK