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Regulation of Transcription of Genes Colding for Light-harvesting Proteins in Phytoplankton under Fluctuating Light Conditions

Project goals

Photosynthesis is regulated at different levels under influence of fluctuating light intensity, temperature and nutrient availability. One of the regulation level are changes in cellular pigment content, associated with the synthesis and degradation of proteins of light-harvesting antennae. These can be divided accordint to the associated secondary pigments (LHC for chla/b,FCP for chla/c and fucoxanthin, PCP for chl a and peridinine). Light-harvesting antennae are composed from several homologous proteins encoded in nucleus. Although the exact reasons for multiple LHC proteins are not known, it is assumed thet each of those proteins has distinct role. Only little is known about a) light-harvesting regulation mechanisms in fluctuating light environments, b) regulation of LHC, FCP a PCP complexes, c) regulation of particular homologous proteins. The proposed project will focus on answerint these questions using modern methods of molecular biology.

Keywords

light-harvesting complexesfluctuating lightgene experssionpigmentsLHCFCPPCPhomologous light-harvesting protein familyredox sensorsplastoquinon poolthioredoxin/ferrodoxin cascadevariable fluorescence

Public support

  • Provider

    Academy of Sciences of the Czech Republic

  • Programme

    The research grant projects for juniors

  • Call for proposals

    Juniorské badatelské grantové projekty 3 (SAV02005-J)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    KJB600200515

Alternative language

  • Project name in Czech

    Regulace genů kódujících proteiny fotosyntetických antén u řas v proměnném světelném prostředí

  • Annotation in Czech

    Fotosyntéza je regulována na různých úrovních v závislosti na intenzitě fluktuujících světla, teploty a dostupnosti živin. Jednou z úrovní regulace je změna buněčné pigmentace, spojená se syntézou a degradací proteinů světlosběrných antén. Světlosběrné anténní komplexy eukaryotních řas se rozdělují podle toho, jaké sekundární pigmenty jsou v anténách navázány (LHC pro chla/b, FCP pro chla/c a fucoxanthin, PCP u chla a peridininu). Světlosběrné antény obsahují několik homologních proteinů kódovaných v jádře. Ačkoliv přesné důvody pro multiplicitu LHC proteinů nejsou dosud jasné, předpokládá se, že každý z těchto proteinů má jednoznačnou funkci. Téměř nic není známo a) o mechanismech regulace světlosběrných antén v přirozených podmínkách proměnné intenzity ozářenosti, b) o rozdílech v regulaci LHC, FCP a PCP komplexů, c) o regulaci jednotlivých homologních proteinů. Tyto problémy budeme v navrhovaném projektu studovat pomocí moderních metod molekulární biologie.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    EE - Microbiology, virology

  • CEP - another secondary branch

    EI - Biotechnology and bionics

  • 10603 - Genetics and heredity (medical genetics to be 3)
    10604 - Reproductive biology (medical aspects to be 3)
    10605 - Developmental biology
    10606 - Microbiology
    10607 - Virology
    10608 - Biochemistry and molecular biology
    10609 - Biochemical research methods
    20801 - Environmental biotechnology
    20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management
    20803 - Environmental biotechnology related ethics
    20901 - Industrial biotechnology
    20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
    20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
    30101 - Human genetics
    30401 - Health-related biotechnology
    30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
    30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])
    30404 - Biomaterials (as related to medical implants, devices, sensors)
    30405 - Medical biotechnology related ethics
    40401 - Agricultural biotechnology and food biotechnology
    40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
    40403 - Agricultural biotechnology related ethics

Completed project evaluation

  • Provider evaluation

    O - Nesplněno zadání, smlouva však byla dodržena

  • Project results evaluation

    While some partial succes in the experimental part of the project has been reached, the results of the project have not been published in any scientific periodical as yet.

Solution timeline

  • Realization period - beginning

    Jan 1, 2005

  • Realization period - end

    Dec 1, 2007

  • Project status

    U - Finished project

  • Latest support payment

    Feb 27, 2007

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP08-AV0-KJ-U/02:2

  • Data delivery date

    Apr 3, 2009

Finance

  • Total approved costs

    1,790 thou. CZK

  • Public financial support

    1,790 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK

Recognised costs

1 790 CZK thou.

Public support

1 790 CZK thou.

0%


Provider

Academy of Sciences of the Czech Republic

CEP

EB - Genetics and molecular biology

Solution period

01. 01. 2005 - 01. 12. 2007